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Academy

Animal first aid.

Read this first. This is information, not treatment. Every dose on this page is a published label range, shown so that you can read a prescription and catch an arithmetic error, not so that you can write one. In India a medicine marked Rx (Schedule H or H1) is sold only against a registered practitioner's prescription, and veterinary medicine may be practised only by a registered veterinary practitioner. Where a lesson says "vet now", it means the nearest veterinary hospital, college clinic or registered vet, today, not tomorrow.

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The biology underneath

Short films that sit beside the modules, made by other people and credited to them. They play here, with the same controls as the rest of the site.

The syllabus

Ten modules, in the order a rescuer meets them.

Seventy-six lessons across the ten. Each lesson shows its key point without being opened; the detail, the tables and the sources are one tap further in. Search or filter to pull a single topic out of the whole.

01

Foundations: how to read a medicine

Generic names, strengths, Schedule H, routes, why a cat is not a small dog, and how to store medicine in Indian heat.

7 lessons12 min
02

Medicines: the classes you will meet

Painkillers, steroids, dewormers, tick and flea products, gut drugs, fluids, hormones, and the street-dog conditions of India.

8 lessons16 min
03

Antibiotics and resistance

What they do and do not touch, the classes on Indian prescriptions, the five rules of a course, and the laws that now govern them.

7 lessons14 min
04

Vaccines

Dogs, cats, community dogs, cattle and buffalo, goats and sheep, horses: the Indian schedules, the cold chain, and why vaccines fail.

9 lessons18 min
05

Antivenom and snakebite

The Big Four, what Indian polyvalent antivenom neutralises, how dose is decided, and the first aid that helps rather than harms.

7 lessons12 min
06

Immunoglobulins: borrowed immunity

Rabies immunoglobulin and monoclonals, antivenom, tetanus antitoxin, colostrum, and why puppy vaccines are a series.

7 lessons12 min
07

First aid: the first hour

Approach, the sixty-second check, road accidents, wounds and maggots, heatstroke, poisoning, burns, newborns, cattle emergencies, the kit.

14 lessons28 min
08

Dosages: the arithmetic

Milligrams per kilogram, tablets and millilitres, the decimal point, a checker for the prescription in your hand, and a reference table.

7 lessons16 min
09

Indications, contraindications, interactions

What a drug is for, when it must not be given, which pairs fight, and how food and timing change a dose.

6 lessons14 min
10

Do's and Don'ts

The essential list, an audit of kitchen remedies from turmeric to Dettol, and the ten sentences that get a vet to help you fast.

4 lessons10 min

PFA AcademyFoundations: how to read a medicine

Most harm done to animals with medicine in India is not done by the wrong drug. It is done by the right drug in the wrong strength, by the wrong route, for the wrong species, or from a bottle that spent a summer in a car. This module gives you the vocabulary to avoid all four.

  • Tell a brand name from the molecule inside it and read a strength off any label.
  • Decode a prescription line, including the abbreviations vets use.
  • Say why a cat, a dog, a cow and a horse each need a different rule book.
  • Store vaccines and medicines so that they still work when needed.
1.1What is actually in the box: brand, molecule and strength

Every medicine has one true name, the generic or molecule name, and any number of brand names. The molecule is what acts; the brand is what the shop stocks.

Do this
Do thisBefore giving anything, read three things aloud: the molecule, the strength per tablet or per mL, and the weight of the animal. If any of the three is missing, stop and ask.

Meloxicam is meloxicam whether the carton says Melonex, Metacam or a chemist's own brand. The dangerous variable is not the brand but the strength: how many milligrams of the molecule sit in one tablet or one millilitre. Human meloxicam tablets are 7.5 mg and 15 mg. The veterinary oral suspension for dogs is 1.5 mg per mL, and the injection is usually 5 mg per mL. A 5 kg dog on a correct 0.1 mg per kg dose needs 0.5 mg. One human 7.5 mg tablet is fifteen times that.

The same is true of the antibiotic amoxicillin-clavulanate, which comes as 375 mg and 625 mg human tablets, veterinary 250 mg and 500 mg tablets, and paediatric syrups of several strengths. Reading "give one tablet" without reading which tablet is how overdoses happen.

Basis
1.2Reading an Indian label: Rx, Schedule H, H1, expiry, withdrawal

Indian labels carry a small set of legally fixed phrases. Once you can read them, a strip of tablets tells you how it may be bought, how long it lasts and, for a farm animal, how long its milk or meat must be discarded.

Warning6 facts
CarefulA strip with the Schedule H warning that a shop hands over without a prescription is a shop breaking the law, not a sign the drug is safe to use casually. The warning is on the strip because of what the drug can do.
"Schedule H drug. Warning: To be sold by retail on the prescription of a Registered Medical Practitioner only." Prescription only. Most antibiotics, NSAIDs, steroids and sedatives carry it. The definition of a registered practitioner in the Drugs Rules includes a person engaged in the practice of veterinary medicine, which is why a vet's prescription is enough at a chemist.
Schedule H1, a stricter class introduced in 2014, covers third and fourth generation cephalosporins, carbapenems, anti-tuberculosis drugs and a number of habit-forming drugs. The chemist must record the prescriber, the patient and the drug in a register kept for three years. If a vet prescribes one, expect the pharmacist to ask for the prescription and write it down.
"For veterinary use only" or "For animal treatment only" marks a veterinary licence. It does not make the drug gentler; it means the strength and label were set for animals.
Mfg., Exp., Batch No.Expiry is the last day the manufacturer guarantees potency under the stated storage. A vaccine or an antibiotic past expiry is not a bargain, it is a coin toss.
Withdrawal period on livestock medicines: the number of days after the last dose during which milk must not be sold and the animal must not be slaughtered for food. FSSAI sets residue limits for antibiotics in food; the withdrawal period is how a farmer stays under them.
Storage"Store below 25 °C", "Store at 2 °C to 8 °C, do not freeze", "Protect from light". In an Indian May, "below 25 °C" means a refrigerator or an air-conditioned room, not a shelf.
Basis
1.3Reading a prescription line, and the abbreviations vets use

A complete prescription line answers seven questions: which animal, what weight, which molecule, what strength, how much, by which route, how often and for how long. If one is missing, the line is not complete.

Table

An example, as it might be written for a 12 kg community dog with tick fever: Doxycycline 100 mg tab, 1/2 tab PO BID x 28 days, with food. Read it as: doxycycline, 100 mg tablets, half a tablet, by mouth, twice a day, for twenty-eight days, given with food. Half of 100 mg is 50 mg, which for 12 kg is about 4.2 mg per kg twice daily, inside the published range of 5 mg per kg twice a day or 10 mg per kg once a day. The arithmetic is checkable, which is the point of writing it out.

The abbreviations are Latin shorthand and every vet in India uses them:

WrittenMeansWrittenMeans
POby mouthOD or SIDonce a day
SC or S/Cunder the skinBIDtwice a day, 12 hours apart
IMinto muscleTIDthree times a day, 8 hours apart
IVinto a veinQIDfour times a day
q8h, q12h, q24hevery 8, 12, 24 hoursEODevery other day
prnas needed, within a stated limitstatat once, one dose now
tab, captablet, capsulesusp, syrsuspension (shake), syrup
mg/kgmilligrams per kilogram of body weightmLmillilitre, the volume of a liquid

Dose is the amount given at one time. Dosage is the whole plan: dose, route, interval and duration. When a vet says "the dosage is 5 mg per kg BID for 28 days", each of those four parts is a separate instruction, and each one matters.

Basis
1.4Routes: why the same drug is a different drug by mouth, under the skin and in a vein

The route decides how fast a medicine arrives, how much of it arrives, and what it can damage on the way. Changing the route changes the dose, so a route is never a detail to improvise.

Warning6 facts
CarefulNever give an injectable by mouth or an oral liquid by injection, never inject anything into a vein yourself, and never put anything into the mouth of an animal that is unconscious, fitting or vomiting: it goes into the lungs.
By mouth (PO)slowest, safest for a layperson, and the only route a caregiver should ordinarily use. Some drugs are destroyed in the stomach or the rumen, which is why a cow's oral dose can differ so much from a dog's.
Under the skin (SC)most vaccines and fluids for dehydration. Absorbed over minutes to hours. Some irritant drugs cause an abscess or a slough if given this way.
Into muscle (IM)faster than SC; painful for some drugs; a wrong site in a hind leg can hit the sciatic nerve.
Into a vein (IV)immediate and complete. Antivenom, anaesthetics, calcium for milk fever and most emergency drugs go IV, and an IV drug given too fast, or a drug never meant for a vein, can stop a heart. This route belongs to a vet.
Topical, spot-on, pour-on, diptick and flea products, wound antiseptics. Dosed by weight band and, for cattle, along the back. What is safe on a dog's skin can kill the cat that grooms him.
Intramammarymastitis tubes, into the teat canal, after cleaning the teat end. Milk from that quarter is discarded for the label period.
Basis
1.5A cat is not a small dog, and a cow is not a large one

Species differ in the enzymes that break drugs down, in the way their guts work and in which organs a drug reaches. The differences are large enough to be fatal, and they are the reason the word "safe" never travels between species.

Do this5 facts
Do thisWhen you call a vet about a medicine, say the species first, then the weight, then the drug. A vet cannot give you a safe answer without the first word.
Cats have very little of the liver enzyme (glucuronyl transferase) that dogs and humans use to detoxify many drugs. Paracetamol, aspirin, permethrin, benzyl alcohol, phenolic disinfectants such as Dettol and many essential oils are dangerous to cats at doses that dogs tolerate. Cats also cannot make their own taurine or vitamin A and must not be fed as small dogs.
Dogs are the species most often poisoned by human painkillers because they share our homes. Ibuprofen, diclofenac and naproxen cause stomach ulcers and kidney failure at doses that look small. Some herding breeds carry a gene defect (MDR1, also written ABCB1) that lets ivermectin and related drugs into the brain.
Cattle, buffalo, goats and sheep are ruminants: an oral drug meets a forty-litre fermentation vat first, so many drugs are given by injection or as drenches designed for the rumen. Anything that stops the rumen (a wrong antibiotic, a fever, a plastic bag) becomes its own emergency. And whatever they receive can end up in milk.
Horses and donkeys cannot vomit and have a gut that twists easily; several antibiotics that are routine in dogs cause fatal colitis in horses. Tetanus is a far greater risk in equines than in any other domestic species.
Birds and rabbits have their own lists; a drug that is a standard antibiotic in a dog can kill a rabbit's gut flora and the rabbit with it.
Basis
1.6Who may prescribe, who may give, and what a layperson may do

The Indian Veterinary Council Act 1984 reserves the practice of veterinary medicine to registered veterinary practitioners, with a narrow allowance for State-permitted minor veterinary services. A rescuer may give first aid and may give a medicine a vet has prescribed, exactly as prescribed.

4 facts
Recognise an emergency, give first aid, and move the animal to a vet safely (Module 07).
Give medicines a vet has prescribed, at the right dose, route, time and duration, and check the arithmetic (Module 08).
Apply licensed over-the-counter products on the label's terms: a deworming tablet at the label dose, a tick spot-on for the right species and weight band, an antiseptic.
Keep records: weights, dates, batch numbers, what was given and how the animal responded. Records make the next vet visit shorter and safer.

Section 57 of the Act makes it an offence for anyone else to practise veterinary medicine, and the definition of veterinary medicine is wide: modern scientific veterinary medicine in all its branches, including surgery and obstetrics. Choosing a drug, a dose and a course for an animal is practice. Following a prescription is not.

What a caregiver may properly do, and what this Academy is written to help with:

Community dog vaccination, sterilisation and treatment programmes run under the Animal Birth Control Rules 2023 are carried out by or under veterinarians for the same reason: the medicines are safe in trained hands and the animals cannot speak for themselves.

Basis
1.7Storage in Indian heat: the cold chain, the eight-hour rule, the car

Biologicals die quietly. A vaccine that spent an afternoon at 40 °C looks exactly like one that did not, and the animal it fails to protect finds out months later.

Warning6 facts
CarefulA parked car in an Indian summer exceeds 60 °C inside. Nothing biological survives it. A rescue kit that lives in a vehicle should hold no vaccines and no antivenom, only what the label allows to be kept warm.
Vaccines live at 2 °C to 8 °C, in the body of a refrigerator, never the door and never the freezer compartment. Liquid (adsorbed) vaccines are destroyed by freezing; freeze-dried ones survive it but their diluent ampoules crack. Carry them in an insulated box with ice packs that do not touch the vials.
Reconstituted vaccine is used at once. The national rabies guidelines set eight hours at 2 °C to 8 °C as the absolute limit for an opened, reconstituted vial, after which it is discarded.
Antivenomthe freeze-dried form keeps for five years in a cool dark place; the liquid form needs 2 °C to 8 °C, keeps two years, and must not be frozen.
Insulin, some eye drops, probiotics, hyperimmune serarefrigerated, and the label says so.
Tablets and capsulesdry, dark, below 25 °C. Blister strips are not airtight once one pocket is broken.
Oral suspensionsshake before every dose. The drug settles; the first spoonful from an unshaken bottle is water and the last is a triple dose.
Basis

Check yourself

Module 01
A vet writes "Meloxicam susp 1.5 mg/mL, 0.1 mg/kg OD" for a 10 kg dog. A relative offers a human 7.5 mg meloxicam tablet, saying it is the same medicine. Is it the same dose?
Which sentence about the Schedule H warning is true?
A reconstituted rabies vaccine vial was opened at 9 am and kept in the refrigerator. It is now 7 pm. Can it be used?

PFA AcademyMedicines: the classes you will meet

A prescription for a street dog or a village cow in India draws on a short list of drug classes. Knowing what each class does, and what it is known to break, is most of what a caregiver needs to follow a treatment intelligently and to notice when something is going wrong.

  • Name what a painkiller, a steroid, a dewormer and an antiemetic each do, and their signature risks.
  • Explain why four veterinary painkillers are banned in India and which one is used instead.
  • Recognise the six conditions that account for most sick street dogs and what treating them involves.
2.1Pain and inflammation: NSAIDs, and the four that India has banned for animals

Non-steroidal anti-inflammatory drugs (NSAIDs) block the enzymes that make prostaglandins, which is how they take away pain, fever and swelling. The same prostaglandins protect the stomach lining and keep blood flowing through the kidney, which is where every NSAID does its damage.

Warning
CarefulHuman NSAIDs are not a substitute. Ibuprofen causes stomach ulcers in dogs at around 100 mg per kg and kidney failure from about 175 mg per kg; a 200 mg tablet is enough to hurt a small dog, and cats are harmed at half those doses. Paracetamol is a poison to cats at any dose and is not a pain reliever anyone should give a dog without a vet. Aspirin is toxic to cats and of limited use in dogs.

The veterinary NSAIDs a vet in India reaches for are meloxicam Rx (dogs, cats with great care, cattle, buffalo), carprofen and firocoxib (dogs), tolfenamic acid (dogs, cats, cattle), flunixin (cattle, horses) and phenylbutazone (horses). All are given with food, with the animal drinking normally, and never alongside a steroid or a second NSAID. The warning signs of trouble are vomiting, black or tarry stool, refusing food, and drinking or urinating more than before; any of these means the drug stops and the vet is told the same day.

India has removed four NSAIDs from veterinary use because of what they did to vultures, which died of kidney failure after eating carcasses of treated cattle: diclofenac (withdrawn from veterinary use in 2006, with the formal prohibition under Section 26A of the Drugs and Cosmetics Act gazetted in 2008), ketoprofen and aceclofenac (notification of 31 July 2023), and nimesulide (gazetted in January 2025). Aceclofenac turns into diclofenac inside a cow. Meloxicam is the vulture-safe alternative and is what the Vulture Recovery Plan recommended in place of diclofenac.

Basis
2.2Steroids: the most useful and most misused injection in India

Corticosteroids such as prednisolone and dexamethasone Rx suppress inflammation and the immune system. In the right hands they treat allergy, immune-mediated disease, some cancers and shock. In the wrong hands they hide an infection, delay healing and cause a second disease.

Do this
Do thisIf an animal has been on steroids for more than a week or two, never stop suddenly. The vet tapers the dose so the adrenal glands can restart; ask for the taper schedule in writing.

At anti-inflammatory doses (prednisolone around 0.5 to 1 mg per kg a day in dogs) they relieve itch and swelling; at immunosuppressive doses (2 to 4 mg per kg a day) they switch off the immune response, which is intended in immune-mediated anaemia and dangerous in an infection. Predictable effects are thirst, hunger, more urine, panting and a thin coat; longer courses bring muscle loss, a pot belly, skin infections and, in cats, diabetes. Steroids and NSAIDs together ulcerate the gut; this pair is the single most common dangerous combination in animal medicine.

Two Indian specifics. Dexamethasone in the last trimester of a cow or buffalo's pregnancy can bring on calving and abortion. And the "one dexa injection" given to any animal that looks unwell, without a diagnosis, is how a treatable infection is masked until it is untreatable.

Basis
2.3Antiparasitics: dewormers, tick and flea products, and the two that must never touch a cat

Parasites are the commonest treatable disease in Indian animals, and antiparasitic drugs are the class a caregiver is most likely to handle. Most are safe on the label's terms; the deaths come from using a dog product on a cat, or a livestock product on a pet.

WarningDo this
CarefulPermethrin and other concentrated pyrethroids, and amitraz, cause tremors, seizures and death in cats, including a cat that grooms a freshly treated dog. Ivermectin at mange doses can be fatal to Collies, Australian Shepherds, Shelties and their crosses, which carry the MDR1 gene defect; the signs are wobbling, dilated pupils, drooling, blindness and coma. Any dog of unknown breeding treated with ivermectin should be watched, and the drug is a vet's decision.
Do thisChildren who play with a dewormed dog are safer than children who play with one that was not. Roundworm and hookworm pass to people through soil and skin. Pick up faeces and deworm on schedule; this is public health.

Worms. Pyrantel (roundworm, hookworm), praziquantel (tapeworm, including the Echinococcus that causes hydatid disease in people) and fenbendazole (a three-day course; also for Giardia) are the usual dog and cat dewormers OTC in India; combination tablets are dosed by weight band on the label. Puppies are dewormed from two to three weeks of age and every two weeks until weaning, then monthly to six months. Livestock get albendazole, fenbendazole, levamisole, ivermectin, and closantel or triclabendazole for liver fluke in flood-prone districts; the ICAR goat calendar recommends deworming before and after the monsoon and at least fifteen days before vaccinating.

Ticks and fleas. Fipronil spot-ons (dogs and cats), imidacloprid, selamectin, and the newer isoxazoline chews (fluralaner, sarolaner, afoxolaner) Rx, which also treat sarcoptic and demodectic mange in dogs and have made ivermectin injections for mange largely unnecessary. Deltamethrin collars and cattle pour-ons, and amitraz dips, are for dogs and livestock only.

Basis
2.4Antihistamines: what they can and cannot do about an itch

Antihistamines block one messenger of allergy. They help with an acute reaction, a wasp sting, a vaccine lump, mild hives. They do little for the chronic scratching of mange, fleas or food allergy, where the itch has another cause that the drug does not touch.

Do this
Do thisAn animal that scratches for more than a few days needs a cause found, not a stronger antihistamine: look for fleas and ticks, skin scrape for mites, ask about diet. Treating the cause ends the itch; treating the itch alone never does.

The ones on Indian prescriptions are chlorpheniramine, cetirizine and diphenhydramine by mouth, and pheniramine (widely sold as Avil) by injection, which vets use for acute allergic reactions and sometimes to blunt reactions to antivenom. Sedation is the main side effect; in cats chlorpheniramine can cause excitement instead. Human "cold and flu" tablets that combine an antihistamine with a decongestant (pseudoephedrine, phenylephrine) are dangerous to dogs and cats and must not be used.

Basis
2.5Stomach and gut: antiemetics, antacids, and why a vomiting puppy is a same-day case

Vomiting and diarrhoea are symptoms, not diagnoses. The gut drugs on a prescription buy comfort and time while the cause is found and fluids are replaced; they do not cure anything by themselves.

Warning4 facts
CarefulA puppy or an unvaccinated young dog that vomits, refuses food and passes foul or bloody diarrhoea is a parvovirus case until proved otherwise, and parvovirus kills by dehydration within days. That animal needs fluids from a vet today, not an antiemetic tablet and a wait.
AntiemeticsRx: maropitant (an injection or tablet given once a day), ondansetron, metoclopramide. Metoclopramide is not given if a blockage is possible, because it drives the gut against the obstruction.
Acid blockersomeprazole, pantoprazole, famotidine. Useful with NSAID injury, kidney disease and reflux; not a reason to keep an animal on an NSAID that is hurting it.
Sucralfate coats ulcers and must be given two hours away from other drugs, which it also coats.
Antidiarrhoealsloperamide has a narrow place in dogs and none in cats or MDR1 breeds; it is never used when the diarrhoea is infectious or bloody. Kaolin-pectin preparations and probiotics are gentle and of modest effect.
Basis
2.6Fluids: reading dehydration, and what may be given by mouth

Dehydration kills more sick animals in India than the diseases that caused it. It is also the one thing a caregiver can measure at the roadside, with two fingers and a watch.

Full explanation

Lift the skin over the shoulder blades and let go. In a hydrated animal it snaps back at once; in a dehydrated one it stands or sinks slowly (the "skin tent"). Press a finger on the gum until it whitens and release: colour should return in under two seconds. Gums that are dry and tacky, eyes that look sunken, and a heart racing faster than the ranges in Lesson 7.2 all point the same way.

What a caregiver may do: offer water, or an oral rehydration solution if a vet has advised it, to an animal that is conscious, can swallow and is not vomiting. Small amounts often, never forced by syringe into a mouth that cannot swallow. What belongs to the vet: fluids under the skin (common for a dehydrated dog or cat that is still drinking a little) and fluids into a vein, where the rate is calculated for the animal's weight and a wrong rate drowns a small animal from the inside.

Basis
2.7Hormones: oxytocin in the dairy, and the contraceptive injection that causes cancer

Two hormone products are misused on Indian animals at scale. One is a crime under the cruelty law; the other is a slow way to give a dog a fatal disease.

Full explanation

Oxytocin Rx is a Schedule H hormone with real uses in labour and in retained placenta, under a vet. Injected into a cow or buffalo to force milk let-down it causes pain, does not make more milk, damages the reproductive tract, and is an offence: Section 12 of the Prevention of Cruelty to Animals Act 1960 punishes anyone who performs "phooka" or "doom dev" or any operation, including the injection of any substance, to improve lactation in a way injurious to the animal, and the animal is forfeited to the government. Its retail sale has been repeatedly restricted by the Centre for exactly this reason.

Hormonal contraceptive injections for dogs, usually medroxyprogesterone acetate, stop heat cycles for a season. They also cause pyometra (a pus-filled uterus that kills), mammary tumours and diabetes. Sterilisation, which the Animal Birth Control Rules 2023 make the lawful way to manage community dogs, removes the uterus and the risk with it. There is no safe "injection instead of surgery".

Basis
2.8The six conditions behind most sick street dogs, and what treating each involves

A colony caregiver will meet the same six diseases over and over. None of them is treated with a single injection, and each has a medicine or a rule that is easy to get wrong.

6 factsCase file
Tick fever.Ehrlichia canis (fever, nosebleeds, bruising, low platelets), Babesia (anaemia, pale gums, dark urine, jaundice) and Anaplasma, all carried by the brown dog tick. Ehrlichiosis is treated with doxycycline Rx for a full 28 days; babesiosis with diminazene or imidocarb injections that only a vet gives, because the margin between the dose and a toxic dose is narrow. Tick control is the prevention.
Parvovirus.Puppies six weeks to six months, sudden vomiting and bloody, foul diarrhoea. No drug kills the virus; survival is fluids, control of vomiting, warmth, and antibiotics because bacteria cross the damaged gut. The virus lives in soil for months; bleach at one part in thirty is what cleans it. The vaccine series prevents it.
Distemper.Cough, discharge, then twitching and seizures weeks later. Supportive care only; a dog that develops fits rarely recovers. The vaccine series prevents it.
Transmissible venereal tumour.A bleeding, cauliflower-like growth on the genitals, spread by mating. It responds well to vincristine Vet only, a cytotoxic drug given into a vein once a week for several weeks; it must not touch skin, and a dose that leaks outside the vein destroys the tissue around it.
Mange.Sarcoptic (intense itch, crusted ear edges and elbows, contagious to people as a short-lived rash) and demodectic (bald patches, little itch, often in the young or the run-down). Isoxazoline chews or ivermectin under a vet, medicated washes, and treating every dog in contact. Neem oil alone does not cure it.
Maggot wounds (myiasis).Fly larvae in any open wound, ear or the vulva of a bitch in heat, worst in the monsoon. Treated by killing and removing every larva, cleaning, dressing, antibiotics and fly control; Lesson 7.4 covers the first aid.
Case file

A 14 kg community dog in October: off food for three days, a nosebleed, small purple spots on the gums. The vet finds a platelet count of 22,000 and starts doxycycline 100 mg, one and a half tablets once a day (about 10 mg per kg) for 28 days, with food, and a tick product.

By day ten the dog is eating and bright. The temptation is to stop. The published course is 28 days because a shorter one lets Ehrlichia persist and relapse, often as the chronic form with bone-marrow failure. The tablet is given with food and a little water because doxycycline burns the gullet if it lodges.

Basis

Check yourself

Module 02
A cow with a swollen knee is limping. Which painkiller may a vet lawfully use in India?
A dog on prednisolone for a skin allergy develops a limp. A relative suggests adding a meloxicam tablet. What is the risk?
A cat has fleas. The household has a permethrin spot-on bought for the dog. Can a small amount be used on the cat?

PFA AcademyAntibiotics and resistance

Antibiotics are the medicines most often given to Indian animals without a diagnosis, and the ones whose misuse reaches furthest: into the milk on a doorstep, into the soil of a colony, and into the hospital ward where a resistant bacterium eventually turns up in a person. This module is about using them so that they keep working.

  • State what antibiotics act on and the three common conditions they do not treat.
  • Recognise the antibiotic classes on an Indian veterinary prescription and each one's signature risk.
  • Apply the five rules of a course and explain a withdrawal period to a farmer.
3.1What antibiotics do, and the three things they do not

Antibiotics kill bacteria or stop them multiplying. They have no effect on viruses, on fungi or on parasites, which between them cause most of the fevers, coughs and diarrhoeas a caregiver sees.

Warning
CarefulEvery unnecessary course selects for the bacteria that survive it. The resistant strain does not stay in the dog: it moves through faeces into soil and water and onto hands. Antibiotic stewardship in animals is not a courtesy to farmers; it is human medicine.

Parvovirus, distemper, kennel cough (mostly viral), ringworm (a fungus) and worms are not cured by an antibiotic. Sometimes a vet still prescribes one alongside a viral disease, as in parvovirus, where bacteria cross the damaged gut wall and the antibiotic prevents sepsis. That is a vet's judgement about a specific risk, not a reason to buy amoxicillin for every vomiting puppy.

Bactericidal drugs (penicillins, cephalosporins, fluoroquinolones, aminoglycosides, metronidazole) kill; bacteriostatic ones (tetracyclines, macrolides, sulfonamides) hold the bacteria still while the immune system finishes them. The distinction matters in an animal whose immune system is not working, and it is one reason the same infection is treated differently in a healthy adult and a starving puppy.

Basis
3.2The classes on an Indian veterinary prescription, and each one's signature risk

Eight classes account for almost every antibiotic a vet in India prescribes. Each has a niche and a way of hurting the animal it is meant to help.

Table
Class and examplesTypically used forSignature risk, and who must not have it
Penicillinsamoxicillin, amoxicillin-clavulanate, penicillin-streptomycin (cattle)Skin, wound, urinary and dental infections; the usual first choice in dogs and cats.Allergy (rare but real); diarrhoea. Never give oral penicillins to rabbits or guinea pigs. Milk withdrawal in cattle.
Cephalosporinscefalexin, cefadroxil, ceftriaxone (injection), cefovecin (a two-week injection)Skin and soft tissue; ceftriaxone is the injectable used in Indian clinics for sepsis and severe infections.Third-generation cephalosporins are Schedule H1 and on the WHO list of critically important antimicrobials; they are not a first choice for a minor wound.
Tetracyclinesdoxycycline, oxytetracycline (cattle)Tick fever, leptospirosis, respiratory infections; oxytetracycline for many cattle and goat infections.Doxycycline lodged in the gullet causes strictures, especially in cats: give with food and follow with water. Stains growing teeth. Must not be given with antacids, iron, calcium or milk.
Fluoroquinolonesenrofloxacin, marbofloxacin, ciprofloxacinSerious urinary, prostate, deep skin and some gut infections.Damages cartilage in growing puppies (under about a year in large breeds). Enrofloxacin above 5 mg per kg a day causes irreversible blindness in cats. Critically important for humans; a second-line choice.
MetronidazoleAnaerobic infections, dental disease, Giardia, some diarrhoeas.High or long doses cause a wobbling gait, head tilt and seizures. Bitter; cats spit it out. Not in pregnancy.
Aminoglycosidesgentamicin, amikacin, streptomycinSevere Gram-negative infections, usually in hospital.Kidney damage and deafness, worst in a dehydrated animal or with an NSAID or furosemide alongside. Injection only.
Sulfonamidestrimethoprim-sulfaUrinary, respiratory and some protozoal infections; coccidiosis in kids and lambs.Dry eye (KCS) in dogs, blood disorders, kidney crystals if the animal is not drinking; Dobermanns react badly.
Macrolides and othersazithromycin, erythromycin, tylosin (cattle), chloramphenicolRespiratory infections, some skin infections, tylosin for cattle and calves.Chloramphenicol can cause bone-marrow failure in the human handling it: gloves, no crushed tablets in the kitchen. Macrolides given to horses cause fatal colitis.

Colistin, a last-resort human antibiotic, is banned in India for food-producing animals, poultry, aquaculture and feed supplements since 19 July 2019. It has no place in a dairy or a poultry shed.

Basis
3.3The five rules of a course

Right diagnosis, right drug, right dose, right interval, right duration. Miss one and the course fails or breeds resistance; miss two and the animal is worse off than untreated.

Warning5 steps
CarefulLeftover antibiotics are not a medicine chest. A half-strip saved from one dog's course, given to another for a different infection at a guessed dose, is the textbook way to breed a resistant strain and to miss a diagnosis.
  1. Diagnosis first.An antibiotic is chosen for a bacterium, not for a symptom. "Fever" is not a diagnosis.
  2. Drug fitted to the bacterium and the site.Skin, urine, gut, bone and brain each admit different drugs. The vet's choice of a "weaker" older drug is usually stewardship, not stinginess.
  3. Dose by weight.Under-dosing is the classic resistance-breeder: enough drug to select survivors, not enough to kill them. The tablet made for a 30 kg dog is not "a bit strong" for a 6 kg one; it is five times the dose.
  4. Interval matters.Twice a day means every twelve hours. A drug given at 8 am and 2 pm and then nothing till the next morning spends half its time below the level that works.
  5. Duration as prescribed.The published course length is the shortest one shown to clear the infection. Stopping when the animal looks better leaves the hardiest bacteria alive.
Basis
3.4Culture and sensitivity: what the test is, and when it is not a luxury

A culture grows the bacteria from a swab, urine or pus; a sensitivity test shows which antibiotics kill that particular strain. It turns guessing into knowing, and it is available at veterinary colleges and many city laboratories.

Do this
Do thisIf a vet suggests a culture for a recurring infection, say yes. If a dog is on its third course of a different antibiotic for the same wound, ask for one.

It is not needed for a first, uncomplicated skin or wound infection. It is needed, and is cheaper than another failed course, when an infection comes back, when it has not improved after a proper course, when it is deep (bone, prostate, kidney, an old maggot wound), when the animal is very sick, or when a reserve antibiotic is being considered. The sample must be taken before the first dose, or the result is a list of what the antibiotic did not kill.

Basis
3.5Resistance and the law: Schedule H1, the colistin ban, and residue limits

India adopted a National Action Plan on Antimicrobial Resistance in 2017 and has since used the Drugs and Cosmetics Act to fence off the antibiotics that matter most. A caregiver or farmer meets three of those fences.

3 facts
Schedule H1 (2014).Third and fourth generation cephalosporins, carbapenems and other reserve drugs may be sold only against a prescription that the chemist records in a register, kept for three years. A vet who prescribes ceftriaxone for a dog is operating inside this rule.
The colistin ban (19 July 2019).The manufacture, sale and distribution of colistin and its formulations for food-producing animals, poultry, aquaculture and feed supplements is prohibited outright, and every colistin pack must say so. Its use as a growth promoter in poultry was the reason.
FSSAI residue limits.The Food Safety and Standards (Contaminants, Toxins and Residues) Regulations set maximum residue limits for antibiotics in milk, meat, eggs and fish. Milk from a treated cow sold before the withdrawal period is over breaks them.

The World Health Organization ranks fluoroquinolones, third-generation cephalosporins, macrolides, colistin and glycopeptides as critically important for human medicine. When a vet chooses amoxicillin over enrofloxacin for a wound, that ranking is why.

Basis
3.6Cattle, buffalo and goats: withdrawal periods, mastitis tubes, and the milk you must not sell

Every antibiotic given to a milking animal appears in her milk for days afterwards. The withdrawal period on the label is the count of those days. Selling the milk earlier puts the drug into children and breaks the food law.

Do this3 facts
Do thisAsk the vet two questions after any injection or tube: "When can I sell the milk?" and "When could this animal be sold for meat?" Write both dates on the wall of the shed.
Milk from a treated quarter or a treated animal is milked out and discarded, not fed to calves raw, not mixed into the pooled can.
The dry-cow period is when persistent infections are treated with long-acting tubes, because there is no milk to discard.
Ear-tag numbers under the national livestock programme make a treatment record possible; use it.

Typical Indian dairy antibiotics are oxytetracycline, penicillin-streptomycin, enrofloxacin, ceftriaxone, and intramammary tubes for mastitis (a syringe of antibiotic pushed into the teat canal after the teat end is cleaned). Each carries a milk withdrawal, usually two to five days after the last dose, and a longer meat withdrawal. The label is specific to the product; a vet writes the discard date on the treatment record.

Basis
3.7Antiseptics are not antibiotics: what to put on a wound, and what never to

An antiseptic kills germs on a surface. It is the right thing for a fresh wound, and the wrong thing for most of what Indian households actually pour on one.

Do this
Do thisThe three things worth carrying in a rescue kit for wounds are a bottle of clean water or saline, povidone-iodine, and clean gauze. Nothing from the kitchen.

Use: clean running water first, in quantity; then povidone-iodine diluted to the colour of weak tea, or chlorhexidine at a wound-safe dilution. Both are cheap and available at every chemist. A clean, damp dressing and a trip to the vet complete the first aid. Antibiotic ointments have a small place on superficial scrapes and none on deep or maggot wounds, where they trap what needs to drain.

Never use: undiluted spirit or hydrogen peroxide in a deep wound (they kill the tissue that has to heal), phenyl or Dettol on a cat (phenolic disinfectants are toxic to cats), kerosene or petrol on maggots (they burn), turmeric, neem paste, ghee, coffee powder or tobacco (they seal in bacteria, hide the wound from the vet, and, in bite wounds, the national rabies guidelines specifically warn against applying irritants such as soil, chillies, oil, lime, herbs, chalk and betel leaves, and turmeric belongs on the same list: they damage tissue and give a false sense of treatment).

Basis

Check yourself

Module 03
A two-month-old puppy has watery diarrhoea and is vomiting. A neighbour offers a strip of amoxicillin left over from his dog. What is wrong with this plan?
A cat with a urinary infection is prescribed enrofloxacin. Why does the vet insist the dose stays at or below 5 mg per kg a day?
A buffalo was given an oxytetracycline injection yesterday. The label says milk withdrawal is four days. When can her milk be sold?

PFA AcademyVaccines

Vaccination is the cheapest medicine in this Academy and the one most often done incompletely. A puppy given one shot is not "vaccinated"; a cow given FMD vaccine once a year is not covered; a rabies dose kept warm in a bag is water. The schedules below are the Indian ones, with the international guideline they rest on.

  • Explain why puppies and kittens need a series and not a shot, using maternal antibodies.
  • Read the Indian schedules for dogs, cats, cattle, buffalo, goats and sheep.
  • Run a vaccination day that does not waste the vaccine, and list the reasons vaccines fail.
4.1How a vaccine works, and why "one shot" is a myth

A vaccine shows the immune system a harmless version or piece of a germ so that it builds antibodies and memory cells in advance. Protection takes one to two weeks to appear, and for most vaccines it needs more than one dose to become solid and to last.

Full explanation

Live attenuated (modified live) vaccines contain a weakened germ that multiplies a little; they give strong, long immunity from fewer doses but are avoided in pregnant and in very sick animals. Killed (inactivated) vaccines cannot multiply, so they carry an adjuvant to provoke the immune system and need a primary course of two doses and regular boosters. Rabies vaccines for animals in India are killed vaccines.

The reason a puppy needs three or four doses is its mother. Antibodies in the first milk (colostrum) protect a puppy for weeks, and while they last they also neutralise a vaccine before the puppy's own immune system can respond. The level and the fade-out date differ from litter to litter and from puppy to puppy, so a series given every two to four weeks until sixteen weeks of age or later is the only way to be sure one dose lands after the maternal antibodies have gone. A single early dose gives no reliable protection at all.

Core vaccines protect against diseases that every animal of that species should be protected from because they are severe, widespread and often fatal. Non-core vaccines are given on the basis of local risk. In India rabies is core for dogs and cats because the disease is endemic.

Basis
4.2Dogs: the schedule an Indian vet follows

Core for dogs everywhere: distemper (CDV), adenovirus (CAV, which covers infectious hepatitis) and parvovirus (CPV). Core in India because the disease is here: rabies. Recommended in most of India because the disease is here too: leptospirosis.

WarningTable
CarefulThe national rabies guidelines are explicit: a history of vaccination in the biting dog is not a guarantee that it is not rabid, because vaccine failures happen through poor storage, a sick animal or an incomplete course. A bitten person starts post-exposure prophylaxis regardless, and the dog is observed for ten days.
AgeVaccineNotes
6 to 8 weeksFirst core dose (CDV, CAV-2, CPV), often as a puppy distemper-parvo or a combined DHPPiOnly a healthy, dewormed puppy. A single dose at this age protects only the puppies whose maternal antibody has already faded.
Every 2 to 4 weeks after that, until 16 weeks or olderRepeat core (DHPPi); leptospirosis as two doses two to four weeks apart from 8 weeks, per the labelThe final core dose must be at 16 weeks or later. Where money allows one dose only, WSAVA says give it at 16 weeks or beyond.
12 weeks (3 months) or olderRabies, one doseKilled vaccine. Indian labels commonly ask for a booster at one year and then annual revaccination; follow the label on the vial and any municipal licence rule.
26 weeks, or at the latest 12 monthsCore booster, rabies boosterWSAVA 2024 prefers 26 weeks so the minority of puppies still blocked by maternal antibody at 16 weeks are covered without a long gap.
AdultCore (CDV, CAV, CPV) not more often than every 3 years; leptospirosis yearly; rabies per label and lawKennel cough (Bordetella, parainfluenza) for dogs that board or gather. Canine coronavirus vaccine is not recommended.

A titre test for CDV, CAV and CPV from twenty weeks of age can confirm the series worked; a positive result means the dog needs no core booster for three years. Rabies protection is not confirmed by a routine test in practice, which is why records matter so much when a vaccinated dog bites someone.

Basis
4.3Cats and kittens

Core for cats everywhere: panleukopenia (FPV, the cat parvovirus), herpesvirus (FHV) and calicivirus (FCV), given together. Rabies is core in India. Feline leukaemia (FeLV) is recommended for kittens and for any cat that goes outdoors.

Table
AgeVaccineNotes
6 to 8 weeksFirst trivalent core (FPV, FHV, FCV)Healthy, dewormed kitten.
Every 2 to 4 weeks until 16 weeks or olderRepeat core; FeLV as two doses from 8 weeksSame maternal-antibody logic as puppies; the last dose at 16 weeks or later.
12 weeks or olderRabiesBooster at one year, then per label.
26 weeks or 12 monthsCore booster
AdultFPV every 3 years; FHV and FCV every 1 to 3 years by risk; FeLV by risk; rabies per labelA cat that never leaves a flat has a different risk from a colony cat; the vet weighs it.
Basis
4.4Community dogs: the ABC Rules, mass vaccination, and what a caregiver contributes

The Animal Birth Control Rules 2023 make sterilisation and anti-rabies vaccination of community dogs, followed by return to the same place, the lawful way for a local body to manage them. Dog-mediated human rabies ends when enough of the dogs in an area are immune.

4 facts
Knows every dog in the colony, so the vaccination team misses none and the unnotched are presented first.
Keeps a card or a phone note per dog: date of rabies vaccine, batch, who gave it. This is what a bitten neighbour's doctor will ask for.
Reports a dog that changes behaviour, drools, staggers or bites without provocation, so that a vet can assess it and it can be safely confined, observed and cared for.
Takes pre-exposure rabies vaccination personally (Lesson 6.2): a caregiver is bitten sooner or later.

The World Health Organization's figure is that vaccinating about 70 per cent of the dogs in an area, repeated yearly, interrupts transmission. India has committed to eliminating dog-mediated human rabies by 2030 under a national action plan, and mass dog vaccination is the mechanism. Under the Rules a dog that has been through the programme is ear-notched and returned; the notch is the visible record.

What a caregiver does that no programme can do alone:

Basis
4.5Cattle and buffalo: the NDDB schedule and the national programme

Foot and mouth disease and brucellosis are vaccinated free of charge under the National Animal Disease Control Programme, launched in 2019, which aims at controlling FMD and eradicating it by 2030. The rest of the schedule is the farmer's, and the State animal husbandry department's, to keep.

Table
DiseaseFirst doseBoosterThen
Foot and mouth disease (FMD)4 months and above1 month after the first doseEvery six months. Under NADCP the whole bovine, sheep, goat and pig population is vaccinated six-monthly.
Haemorrhagic septicaemia (HS)6 months and abovenoneAnnually in endemic areas, before the monsoon.
Black quarter (BQ)6 months and abovenoneAnnually in endemic areas, before the monsoon; often combined with HS.
Brucellosis (S19 vaccine)Female calves only, 4 to 8 monthsnoneOnce in a lifetime. Never adult animals, never males. Brucellosis is a serious human disease: aborted material is handled with gloves and buried.
Theileriosis3 months and abovenoneOnce in a lifetime; needed for crossbred and exotic cattle only.
Anthrax4 months and abovenoneAnnually in endemic areas, before the monsoon. A suspected anthrax carcass is never opened.
Lumpy skin disease (LSD)Since the 2019 outbreaks India has used goat pox vaccine for cross-protection; the indigenous homologous vaccine Lumpi-ProVacInd, developed by ICAR institutes, is being deployed. Follow the State department's advisory for the current product and interval.
RabiesPost-bite only in cattle: a course started immediately after a suspected bite, on day 0, then days 4, 7, 14 and 28, with an optional dose on day 90. Ask the vet the moment a dog or jackal bites a bovine.

Under NADCP every vaccinated animal carries a twelve-digit ear tag and its record sits on the national livestock portal. Keep the tag legible; it is the animal's vaccination card.

Basis
4.6Goats and sheep: the ICAR calendar

The Central Institute for Research on Goats publishes an annual health calendar. Its first line is worth the rest: kids are protected for their first three months by the colostrum they drink in their first hours, and after that by vaccination.

Table
DiseaseFirst doseBoosterThen
Peste des petits ruminants (PPR)3 monthsnoneEvery 3 years.
Foot and mouth disease3 to 4 months3 to 4 weeks after the firstEvery 6 or 12 months per the manufacturer.
Goat pox (sheep pox vaccine for sheep)3 to 4 months3 to 4 weeks after the firstEvery 12 months. Goat pox vaccine is for goats only.
Enterotoxaemia (ET)3 to 4 months3 to 4 weeks after the firstEvery 6 or 12 months per the manufacturer.
Haemorrhagic septicaemia3 to 4 months3 to 4 weeks after the firstEvery 6 or 12 months per the manufacturer.

The calendar adds two rules that apply to every species: deworm at least fifteen days before vaccinating, so the immune system is not busy with worms, and dip or spray for ticks before and after winter. Screening breeding animals for brucellosis, which passes to people, is the other habit worth keeping alongside it.

Basis
4.7Horses, donkeys and mules: tetanus first

Equines are the most tetanus-prone domestic animals, and working equines in India live among nails, wire and manure. Tetanus toxoid is the one vaccine no horse or donkey should be without.

4 facts
Tetanus toxoida primary course of two doses four to six weeks apart, a booster at one year, then boosters per the label (yearly in most Indian products). A wounded unvaccinated animal also needs tetanus antitoxin (Lesson 6.4).
Rabiesyearly, where dogs and jackals are around, which in India is everywhere.
Equine influenza and other vaccines as required for movement, racing or by the State.
Glanders has no vaccine. It is a notifiable disease under the Prevention and Control of Infectious and Contagious Diseases in Animals Act 2009, controlled by testing and by the humane destruction of positive animals; a horse with nasal ulcers and nodules along the legs is reported, not treated at home.
Basis
4.8Vaccination day: what makes the dose count

A vaccine works only in an animal whose immune system can answer it, given at the right interval, from a vial that has been kept cold. Most of that is decided before the needle.

Do and never

Do

  • Vaccinate a healthy animal: eating, normal temperature, no diarrhoea, no recent heavy stress such as a long transport.
  • Deworm first; the goat calendar says fifteen days before.
  • Check the vial: within date, kept at 2 °C to 8 °C, reconstituted only when the animal is in front of you.
  • Stay twenty to thirty minutes afterwards. Swelling of the face, hives, vomiting or collapse is anaphylaxis and the vet has adrenaline for it.
  • Write it down: date, vaccine, batch number, who gave it. Expect a small lump and a quiet day; these pass.

Don't

  • Vaccinate an animal with a fever, in the middle of parvovirus, or on high-dose steroids; the vaccine will not take.
  • Give live vaccines to a pregnant animal unless the label allows it.
  • Mix vaccines in one syringe unless they are sold to be mixed.
  • Split one dose between two small animals. The dose is the dose whatever the weight.
  • Vaccinate from a vial that has been warm, cloudy or opened for more than the label allows.
Basis
4.9Why vaccines fail, and how to tell that one did

A vaccinated animal that gets the disease is almost never proof that the vaccine was bad. It is usually proof of one of six things that happened to the vaccine or the animal.

6 steps
  1. Maternal antibody was still present at the last dose: the series stopped too early, or a puppy was given one shot and called done.
  2. The cold chain broke, somewhere between the factory and the syringe.
  3. The interval was wrongdoses too close together do not add up, and a second dose of a killed vaccine given months late is a first dose again.
  4. The animal could not respondfever, malnutrition, parvovirus, steroids or another immunosuppressive illness at the time.
  5. The vial was expired, counterfeit, or the wrong product for the species.
  6. Exposure came before immunity dida dog bitten the week after its first rabies dose was not yet protected.

For distemper, adenovirus and parvovirus, a serology (titre) test from twenty weeks of age shows whether a puppy responded; WSAVA supports it as an alternative to an extra dose. For rabies, the practical proof is the record, which is why the national guidelines treat a bite from a "vaccinated" dog without documentation as a bite from an unvaccinated one.

Basis

Check yourself

Module 04
A colony puppy was given a distemper-parvo shot at six weeks. It is now ten weeks old. Is it protected?
Which cattle are given the brucellosis S19 vaccine under the national programme?
A goat is due for its PPR vaccine. It has never been dewormed. What does the ICAR calendar advise?

PFA AcademyAntivenom and snakebite

India's snakebite season is its monsoon, and dogs, cattle and goats are bitten in the same fields and yards as people. The same vial of antivenom treats all of them. The lessons here are about what is in that vial, how its dose is decided, and the ten minutes of first aid that decide whether the antivenom arrives in time.

  • Name the Big Four and say what Indian polyvalent antivenom does and does not neutralise.
  • Explain why antivenom dose follows venom, not body weight, and why it must be given by a vet.
  • Give correct snakebite first aid and refuse the five traditional measures that harm.
5.1The Big Four, and what is in an Indian vial of antivenom

Indian polyvalent anti-snake venom serum is raised in horses against the venoms of the four snakes that cause most deaths in the subcontinent: the spectacled cobra (Naja naja), the common krait (Bungarus caeruleus), Russell's viper (Daboia russelii) and the saw-scaled viper (Echis carinatus).

Full explanation

The standard is written on every vial: one millilitre of reconstituted serum neutralises 0.6 mg of cobra venom, 0.45 mg of krait venom, 0.6 mg of Russell's viper venom and 0.45 mg of saw-scaled viper venom. A vial holds 10 mL. It is made in the public and private sector, among others by the Central Research Institute at Kasauli, Haffkine, Bharat Serums, VINS and Premium Serums, and it is the same product whether the patient is a child or a bullock.

What it does not cover: the king cobra, the hump-nosed pit viper of the Western Ghats and other pit vipers, sea snakes, and other regional species. Venom also varies by region within a species, which is why a Russell's viper bite in one State can respond less well than in another. When the snake is known not to be one of the four, antivenom is a risk without a benefit.

Basis
5.2How antivenom works, and why the dose follows the venom and not the animal

Antivenom is a purified immunoglobulin fragment that binds venom molecules so that they can no longer act. It works only on venom still circulating; damage already done is not undone. So the earlier it is given the more it can do, and the amount needed depends on how much venom the snake injected, not on how large the victim is.

Warning
CarefulAntivenom is given intravenously by a veterinarian. It is never injected at the bite site, never given under the skin or into muscle by a rescuer, and never diluted "to make it go further".

A large viper can inject the same quantity into a 4 kg puppy as into a 60 kg man, and the puppy, with less blood to dilute it, needs at least as much antivenom. The vet judges the starting dose from the species of snake, the speed of the signs and the bedside clotting test, gives it slowly into a vein, and repeats it if bleeding, swelling or weakness keep advancing. There is no correct dose per kilogram of dog, which is why "one vial for a small animal" is not a rule.

Because the serum comes from horses, a minority of patients react to it, from hives to full anaphylaxis, and serum sickness can follow a week later. The vet has adrenaline drawn up before the drip starts; a skin test does not predict who will react. Reaction is a reason for the vet to be ready, not a reason to withhold antivenom from an envenomed animal.

Basis
5.3Recognising envenomation: vipers, cobras and kraits look different

Dogs are bitten on the face and front legs because they investigate; cattle and goats on the muzzle and lower legs because they graze. Not every bite injects venom. What follows in the first hour tells you which snake, and whether to run.

4 factsCase file
Vipers (Russell's, saw-scaled): rapid, painful swelling that spreads up the limb or across the face; oozing from the fang marks; bruising; blood in urine, vomit or from the gums; collapse. Russell's viper attacks the kidneys, and dark urine or none at all in the next day is the sign.
Cobra: pain and local swelling, sometimes a spreading black patch of dead tissue, then drooping eyelids, drooling, weak limbs, difficulty swallowing and slow, shallow breathing.
Krait: almost no local sign. A dog found weak and floppy in the morning, unable to lift its head or breathe deeply, after a night outdoors, is a krait bite until proved otherwise. Kraits bite sleeping animals and people.
Dry bite: fang marks, no progression after an hour or two. Still a vet visit; the decision that no antivenom is needed is the vet's.
Case file

A 10 kg dachshund in Karnataka was brought to a veterinary college hospital with a swollen face, fang marks on the right cheek and blood-tinged fluid oozing from the bite, after a Russell's viper bite. The only abnormal blood value was a low platelet count. It was treated with polyvalent antivenom into a vein, intravenous saline, and supporting drugs for five days, and recovered fully.

The lesson in the report is the order of events: the owner recognised the bite, carried the dog to a hospital that stocked antivenom, and the antivenom went in before the coagulopathy became bleeding.

Basis
5.4First aid: what helps in the first ten minutes, and the five measures that harm

The whole of useful snakebite first aid is to keep the animal still, keep it calm, and get it to antivenom. Everything traditionally done at the bite site delays that and most of it makes the injury worse.

Do and never

Do

  • Move the animal away from the snake without chasing or handling the snake; note its colour and pattern, or photograph it from a distance if that costs no time. Snakes are protected under the Wild Life (Protection) Act 1972; do not kill it.
  • Keep the animal as still as possible and carry it. A dog that walks pumps venom through its lymphatics faster.
  • Take off the collar; a face or neck bite swells within minutes.
  • Note the time of the bite and go straight to the nearest vet or veterinary hospital that stocks antivenom. Telephone ahead so the vial is out of the fridge.
  • If the animal stops breathing and you know how, support its breathing on the way. Krait and cobra kill by paralysing the breathing muscles, and antivenom reverses it.

Don't

  • Tie a tourniquet or a tight cord above the bite. It causes gangrene and does not stop viper venom.
  • Cut the bite or try to suck venom out. Suction removes almost none and the cut bleeds in an animal that may soon be unable to clot.
  • Apply ice, cold water, hot packs or electric shock. Ice worsens tissue death.
  • Apply herbs, "snake stones", lime, kerosene or any paste, or give alcohol or a home remedy by mouth.
  • Wait to see whether symptoms develop. By the time they are obvious, the antivenom has more to do and less time.
Basis
5.5Where the antivenom is, and how to keep it

Antivenom is stocked at government primary and community health centres and district hospitals for people, and at veterinary hospitals, polyclinics and college clinics for animals. It is the same vial. A colony caregiver who lists the nearest two sources before the monsoon has done the most useful thing possible for a snakebite.

Do this
Do thisBefore the rains: write down the nearest veterinary hospital that stocks antivenom, its night number, and the nearest human facility that does the same for the person who will be bitten while handling a snake-bitten dog.

The freeze-dried form keeps for five years in a cool, dark place and is reconstituted with 10 mL of the diluent supplied; the liquid form keeps for two years at 2 °C to 8 °C and must never freeze. Both are protected from light and heat, which rules out the rescue-vehicle glovebox. Reconstituted serum is used at once.

Basis
5.6Cattle, buffalo, goats and horses: the bite you cannot see

Large animals are bitten on the muzzle and lower legs while grazing at dusk, and their thick hide hides the fang marks. Sudden facial swelling in a grazing animal, a swollen leg with no wound, bleeding from the nose or the mouth, or sudden weakness in a goat is a snakebite until proved otherwise.

Full explanation

The particular danger for horses and cattle is a swollen muzzle that closes the nostrils. Horses breathe only through the nose; a vet may need to place a tube to keep the airway open. Treatment is the same antivenom into a vein, fluids, and management of the bleeding and the tissue damage that follows a viper bite.

Basis
5.7Scorpions, bees, wasps and centipedes: no antivenom for animals, and what to do instead

India's red scorpion is a medical emergency for people, and a scorpion antivenom exists for them; for dogs and cats the treatment is supportive, from a vet, and most recover. Bee and wasp stings are usually minor and occasionally cause anaphylaxis.

3 facts
Scorpion: intense pain, restlessness, drooling, a racing heart; in severe cases fluid in the lungs. Pain relief and heart-rate control from a vet; no home remedy shortens it.
Bee, wasp, hornet: scrape a bee sting out sideways with a card rather than squeezing it; a cold compress for a single sting is fine here because there is no tissue-destroying venom. Many stings, or a sting in the mouth or throat, or any facial swelling, vomiting or collapse, is an emergency; the vet gives an antihistamine and, if needed, adrenaline.
Centipede: painful local swelling; wash, watch, vet if it spreads.
Basis

Check yourself

Module 05
A 5 kg puppy and a 30 kg dog are each bitten by a Russell's viper. Which needs the larger antivenom dose?
A dog is bitten on the leg by a cobra in a village. What is the correct first aid?

PFA AcademyImmunoglobulins: borrowed immunity

An immunoglobulin is an antibody given ready-made. It works within hours and fades within weeks, which makes it the right tool for the day of a rabies bite, a snakebite, a deep wound in a horse, or a newborn's first meal, and the wrong tool for anything long-term. This module also covers the one immunoglobulin a caregiver will personally receive.

  • Distinguish passive from active immunity and say when each is used.
  • Describe rabies post-exposure prophylaxis in India well enough to insist on it for yourself.
  • Explain colostrum, tetanus antitoxin and maternal antibody in one sentence each.
6.1Passive and active immunity: hours versus years

A vaccine teaches the body to make its own antibodies: slow to start, long to last. An immunoglobulin lends antibodies made elsewhere: immediate, and gone in weeks. Rabies prophylaxis uses both at once, for exactly that reason.

Full explanation

After a serious bite, rabies immunoglobulin infiltrated into the wound neutralises virus on day zero, while the vaccine given the same day takes about a fortnight to raise the person's own antibodies to the protective level of 0.5 IU per mL. The immunoglobulin covers the gap. Given too late, or in too large a dose, it can blunt the vaccine's response, which is why the national guidelines fix its window and its maximum.

Sources of borrowed antibody: horses (equine rabies immunoglobulin, antivenom, tetanus antitoxin), pooled human plasma (human rabies immunoglobulin), laboratory-made monoclonal antibodies, and the mother, through colostrum.

Basis
6.2Rabies post-exposure prophylaxis for the person who was bitten: the whole protocol

In India every bite by a warm-blooded animal is treated as a possible rabies exposure, and post-exposure prophylaxis is a medical emergency, not something to arrange next week. Rabies is fatal once symptoms begin and entirely preventable before they do.

Do this
Do thisIf you feed or handle community animals, take pre-exposure prophylaxis now: one dose intramuscularly or intradermally on days 0, 7 and 21 or 28. It turns any later bite into a two-dose visit with no immunoglobulin, and it buys time when a bite happens far from a clinic.

Step one, wound washing. Soap or detergent and running water for ten to fifteen minutes, then an antiseptic such as povidone-iodine or alcohol. This alone removes much of the virus. Do not touch the wound with bare hands, do not apply soil, chillies, oil, lime, herbs, chalk or betel leaves (the guidelines' own list), nor turmeric or salt, and do not get it stitched if that can be avoided; if it must be sutured, the immunoglobulin goes in first and the stitches wait a few hours.

Step two, the category. Category I (touching, licks on intact skin) needs no prophylaxis. Category II (nibbling of bare skin, minor scratches without bleeding) needs the vaccine. Category III (any bite that breaks the skin, scratches that bleed, licks on broken skin or on the eyes, nose or mouth, and any bite from a wild animal) needs the vaccine and rabies immunoglobulin.

Step three, the immunoglobulin (Category III, once, on day 0, no later than day 7 of the vaccine course). Equine RIG at 40 IU per kg (Indian ERIG is 300 IU per mL, maximum 3000 IU), or human RIG at 20 IU per kg, or a rabies monoclonal antibody, Rabishield (approved 2016, 3.33 IU per kg) or TwinRab (approved 2019, 40 IU per kg). As much as possible is infiltrated into and around every wound; the rest goes deep into muscle away from the vaccine site. Never in the same syringe or the same limb as the vaccine.

Step four, the vaccine. Either the intramuscular Essen schedule, one dose in the deltoid (thigh in small children, never the buttock) on days 0, 3, 7, 14 and 28, or the intradermal schedule, 0.1 mL at two sites on days 0, 3, 7 and 28, at an anti-rabies clinic that uses it. Someone previously fully vaccinated needs only two doses, on days 0 and 3, and no immunoglobulin. Tetanus toxoid and, if the wound warrants it, an antibiotic are added.

The dog. A dog or cat that can be observed is watched for ten days. If it stays healthy the course may be shortened by the doctor; if it sickens or dies, the course is completed and the animal's head is sent for testing through the veterinary authority. Prophylaxis is never delayed while waiting to see.

Basis
6.3The dog that was bitten: what post-exposure means for an animal

There is no rabies immunoglobulin protocol for animals in India, and no treatment once a dog shows signs. What can be done for a bitten dog depends entirely on its vaccination record.

Warning3 facts
CarefulRabid animals are not always aggressive. A dog that becomes unusually quiet, drools, has a dropped jaw, staggers or seems to be choking needs the same care in handling as one that bites, and the saliva on your hand is the exposure.
A dog with a documented, current rabies vaccination that is bitten by a suspect animal is given a booster at once and watched, usually for 45 days, under the vet's direction.
An unvaccinated dog bitten by a rabid animal needs a veterinarian at once: the vet and the local authority decide the next steps, and the caregiver's part meanwhile is to keep the dog calm, safely confined and apart from people and other animals.
A cow, buffalo or goat bitten by a dog or jackal starts the post-bite course in the NDDB schedule immediately (Lesson 4.5), because rabies in cattle is not rare and is transmissible to the people who milk them.
Basis
6.4Tetanus antitoxin and toxoid: the horse, the wound and the fortnight

Tetanus antitoxin is equine immunoglobulin against the tetanus toxin. Given to a wounded animal that has no vaccine history, it protects for about two weeks, which is long enough for a wound to close and for the toxoid to begin working.

Full explanation

Horses and donkeys are by far the most susceptible domestic animals; cattle, sheep and goats less so; dogs and cats are relatively resistant and rarely need it. The classic cases are a nail in a hoof, a castration or docking done with a dirty blade, a foaling or a deep puncture. The vet gives antitoxin and the first dose of toxoid at the same visit in different sites, then the toxoid course continues (Lesson 4.7). The signs of tetanus itself, stiffness, a locked jaw, a raised tail and the third eyelid flicking across the eye at a noise, appear days to weeks after the wound, and by then treatment is long and often fails.

Basis
6.5Colostrum: the immunoglobulin every newborn must drink in its first hours

Calves, kids, lambs and foals are born with almost no antibodies of their own. Everything that protects them for their first months arrives in the first milk, and the gut can absorb it whole only in the first day of life.

Full explanation

The rule of thumb for a calf is colostrum within the first two hours, and about ten per cent of its body weight over the first day: roughly three to four litres for a 35 kg crossbred calf, in several feeds. By twenty-four hours the gut has closed and antibodies drunk after that are digested as protein, not absorbed. A calf that missed its colostrum is the calf that dies of scours or pneumonia at three weeks. Kids and lambs are the same in miniature; the ICAR goat calendar credits colostrum with protecting kids for their first three months.

Puppies and kittens absorb antibody for their first two to three days. Orphans who missed it are the ones a vet may put on plasma or a hyperimmune serum, and who need their vaccine series started on time. Cow's milk is not a substitute for any of them; a species-appropriate replacer or, for a puppy, a puppy milk replacer, is.

Basis
6.6Hyperimmune sera for parvo and distemper: what the evidence supports

Indian clinics can buy hyperimmune serum or immunoglobulin products raised against canine parvovirus, distemper and adenovirus, sold as an adjunct in the first days of infection. The evidence that they change survival is thin, and they are never a substitute for fluids.

Full explanation

The theory is sound, borrowed antibody against a virus in a puppy that has none, and the products are used by many vets in the first 48 hours of parvovirus. Controlled evidence of benefit is limited, and a puppy that gets serum and no drip still dies of dehydration. The honest position is that they may help early, alongside intensive supportive care, and that the money is better spent on the vaccine series that would have prevented the illness.

Basis
6.7Maternal antibody, again: the reason for every vaccine series

The same borrowed antibody that saves a puppy in its first weeks is what neutralises its early vaccines. Understanding that one fact removes most of the confusion about puppy and kitten schedules.

Full explanation

Maternal antibody falls by half roughly every week to ten days, but the starting level depends on the mother's own immunity and how much colostrum the animal drank. So in one litter a puppy may be open to vaccination at eight weeks and its sibling not until fourteen. The series every two to four weeks until sixteen weeks or older, and the extra dose at twenty-six weeks, exist to catch every puppy on the far side of its own fade-out. It is not over-vaccination; it is the only honest answer to an unknown date.

Basis

Check yourself

Module 06
A volunteer is bitten on the hand by a community dog; the skin is broken and bleeding. Which is the complete response?
A crossbred calf was born at midnight and has not suckled by 9 am. What matters most now?

PFA AcademyFirst aid: the first hour

First aid is what a person with no drugs can do in the hour before a vet, and it decides more outcomes than the drugs do. The rules are the same on a highway, in a cattle shed and on a kitchen floor: keep yourself safe, keep the animal breathing and warm, stop the bleeding, do nothing that hurts, and move.

  • Approach and restrain an injured animal without being bitten, and know when not to try.
  • Take a temperature, a pulse, a breathing rate and a gum reading, and say which numbers mean "vet now".
  • Handle the ten commonest emergencies in Indian rescue work, including the cattle ones.
7.1Approach: keeping yourself unbitten, and the animals you should not touch

A frightened, injured animal may bite out of pain and fear, even as you help it, and in India any bite carries a rabies risk. Your safety is not selfishness: a bitten rescuer cannot get the animal to care.

Do this5 facts
Do thisTake pre-exposure rabies vaccination if you do this work at all. It is three visits, and it turns a bite into a much smaller event.
Approach from the side, low, slowly, talking. Let the animal see your hand. Do not corner it.
Muzzle a conscious dog before moving it: a strip of gauze or soft cloth looped over the snout, crossed under the jaw and tied behind the ears. Never muzzle a dog that is vomiting, struggling to breathe, has a flat face or is overheated. A towel over the head calms most cats; a thick towel wrapped round the body restrains one.
Wear gloves for wounds and for any animal that is drooling. Rabies is in saliva, and broken skin on your hand is an exposure.
Do not handle a dog that is drooling, staggering, snapping at nothing, or unusually quiet with a dropped jaw. Keep people away, call the local body's dog squad or a vet, and if you are exposed, Lesson 6.2 applies today.
On a road, put a person and a vehicle between you and the traffic before you kneel. No rescue is worth being hit for.
Basis
7.2The sixty-second check: breathing, gums, pulse, temperature, and the numbers that mean "vet now"

Four measurements you can take with your hands, a watch and a digital thermometer tell a vet on the telephone almost everything they need to decide how fast to see the animal.

4 stepsTable
  1. Breathing.Count chest rises for 15 seconds and multiply by four. Look at the effort: open-mouth breathing in a cat, a stretched neck, flaring nostrils and a heaving belly are distress at any rate.
  2. Gums.Lift the lip. Pink is normal. Pale or white means blood loss, anaemia or shock; blue means no oxygen; brick red means heatstroke or sepsis; yellow means jaundice (tick fever, liver); brown or muddy means paracetamol poisoning. Press until white and release: colour should return in under two seconds.
  3. Pulse.Fingers flat on the inside of the thigh where it meets the body (the femoral artery), or a hand on the chest behind the elbow. Count for 15 seconds, multiply by four.
  4. Temperature.A digital thermometer, lubricated, gently into the rectum for the time it takes to beep. Over 40 °C or under 37 °C in a dog or cat is an emergency.
SpeciesRectal temperatureResting heart rate (per min)Resting breathing (per min)
Dog37.5 to 39.2 °C70 to 120 puppies and small breeds run faster18 to 34
Cat38.1 to 39.2 °C120 to 140 over 200 in a frightened cat16 to 40
Dairy cow, buffalo38.0 to 39.3 °C48 to 8426 to 50
Goat38.5 to 39.7 °C70 to 80about 15 to 30
Sheep38.3 to 39.9 °C70 to 8016 to 34
Horse, donkey37.2 to 38.2 °C28 to 4010 to 14

Ranges adapted from the Merck Veterinary Manual reference tables (Dukes' Physiology). A value outside the range is a reason to call; a value that is changing fast is a reason to move.

Basis
7.3Road accidents: moving an animal that may have a broken back

Most animals hit by vehicles in India die of what is not visible: internal bleeding, a ruptured bladder, a torn diaphragm, a broken spine. The first aid is to move them without making any of those worse, and to get them to imaging and a drip.

Warning5 steps
CarefulAn animal that can walk after a collision can still have a ruptured bladder or a slow bleed. Any road accident is a vet visit the same day, with a note of the time and what hit it.
  1. Muzzle if conscious (Lesson 7.1). Do not lift by the legs, the scruff or the tail.
  2. Slide the animal onto a flat board, a car mat, a folded blanket or a sheet held taut by two people, keeping the back straight. Two hands under the chest and pelvis for a small animal, carried level.
  3. Press on any bleeding with a clean cloth; cover wounds; keep the animal warm with a blanket even in summer, because shock chills.
  4. Nothing by mouth. A vomiting or unconscious animal inhales it, and an animal with a belly injury may need surgery.
  5. Check the gums every few minutes on the way. Gums going pale, a belly swelling, breathing getting faster and shallower: tell the vet on the phone, because it changes what they prepare.
Basis
7.4Bleeding, wounds, bite wounds, and the maggot wound of the Indian monsoon

Firm, unbroken pressure stops most bleeding within ten minutes. Clean water in quantity does more for a wound than any ointment. And a wound with maggots in it needs every larva out, which is a vet's hour with forceps, not a caregiver's afternoon with turpentine.

Do this4 facts
Do thisPhotograph a wound on day one and every few days. A vet can judge healing from a sequence far better than from a description, and it tells you when a dressing has stopped working.
Bleeding: a pad of clean cloth or gauze, pressed and held. Do not lift it to look; add another layer on top if it soaks through. An object stuck in a wound stays in until a vet removes it; pack around it.
Fresh wounds: flush with clean water or saline until no dirt is visible, then diluted povidone-iodine, then a clean damp dressing. No kitchen products (Lesson 3.7).
Bite wounds from another dog: small holes with large damage beneath. Flush, do not seal, vet within hours for antibiotics and often a drain. The bitten dog's rabies status matters (Lesson 6.3).
Maggot wounds: any wound left open in fly season, and the ears, vulva and anus of the old or sick. Cover the wound to keep more flies off, keep the animal in shade, and get it to a vet the same day. In the clinic each larva is killed and lifted out, often after an ivermectin injection or a larvicidal spray, the cavity is flushed, and antibiotics and fly repellent follow. Turpentine oil, which many field rescuers carry, brings larvae to the surface but does nothing for the wound beneath and burns tissue; kerosene, petrol and phenyl are not treatment at all.
Basis
7.5Fractures: immobilise the animal, not the leg

A badly applied splint does more damage than no splint. The safe first aid for a suspected fracture is to keep the whole animal still and carry it level, and to leave the splinting to the vet with the X-ray.

Full explanation

The signs are a limb held at an angle or dangling, a bone visible or felt under the skin, swelling and severe pain on touch. Cover an open fracture with a clean damp cloth; do not push bone back or wash the wound with anything but saline. Only if the vet is hours away and the break is clearly below the elbow or knee should a padded splint (a rolled newspaper or cardboard, bandaged loosely, joint above and joint below) be considered, and only if the animal tolerates it without struggling.

Basis
7.6Heatstroke: cool first, transport second

Heatstroke kills by cooking organs, and every minute above 41 °C counts. The current veterinary emergency guidance reverses the old advice: cool the animal aggressively where it is, then transport. Wet towels laid over the body and "tepid, not cold, water" are outdated and slow.

Warning5 steps
CarefulNo wet towels over the body (they trap heat once they warm), no ice packs to the skin, no ice baths for old or sick animals. For cattle and buffalo, shade, water sprinkled over the body and fans; a buffalo denied a wallow in May is a heatstroke waiting to happen.
  1. Into shade. Water over the whole body at once: any water cooler than the dog, and for a young, healthy dog, immersion in cold water is the fastest method.
  2. Air movement: a fan, an air-conditioned car, a breeze. Evaporation does the cooling.
  3. Offer water to drink if the animal is conscious; do not force it.
  4. Keep cooling on the way to the vet and stop active cooling when the rectal temperature reaches about 39.4 °C, to avoid overshooting into hypothermia.
  5. Vet regardless of recovery: kidney and gut damage and clotting failure appear over the next day.

The signs are frantic panting, thick drool, brick-red gums, staggering, vomiting or diarrhoea, and collapse; a rectal temperature above 40.5 °C confirms it. The dogs that die are the ones left in cars, chained in the sun, walked at noon, and the flat-faced breeds that cannot pant well; among livestock it is animals in transport and in tin sheds.

Basis
7.7Poisoning: rat poison, insecticide, chocolate, and the human medicine cabinet

The right first aid for almost every poisoning is the same: stop the exposure, keep the packaging, and telephone a vet before doing anything to the animal. Making an animal vomit at home, with salt or anything else, is the intervention that most often kills.

WarningTable
CarefulDo not give salt to induce vomiting: it causes salt poisoning and brain swelling. Do not induce vomiting at all in an animal that is drowsy, fitting or has swallowed a caustic, petroleum or a sharp object. Hydrogen peroxide is used to induce vomiting in dogs only on a vet's instruction, at a stated dose, and never in cats.
PoisonWhat you seeWhat matters
Anticoagulant rat poisonbromadiolone, brodifacoum: the wax cakes and pelletsNothing for two to five days, then weakness, pale gums, nosebleeds, blood in urine, a swollen belly, breathlessness.Treatable with vitamin K1 for weeks if started early; the vet needs the packet name. A dog that ate the bait yesterday and looks well is still a case.
Zinc phosphidethe grey "rat cake" pastesVomiting, gasping, a garlic or fish smell, seizures, within an hour.The vomit releases phosphine gas: keep it outdoors and away from your face. Vet immediately; no home remedy.
Organophosphate and carbamate insecticidesmalathion, chlorpyrifos, carbofuran; also cattle dipsDrooling, tears, urination, diarrhoea, pinpoint pupils, tremors, weakness.The vet has atropine. Wash the coat with soap and water wearing gloves if the exposure was on the skin.
Chocolatedark and baking chocolate are the worstVomiting, restlessness, racing heart, panting, tremors, seizures over hours.Theobromine; dose depends on the type and the dog's weight. Call with both numbers.
Xylitolsugar-free gum, some sweets and syrupsWeakness, wobbling, collapse within an hour; liver failure over days.Blood sugar crashes. Vet at once; tiny amounts matter in a small dog.
Grapes, raisins; onions, garlicVomiting, then kidney failure over days (grapes); weakness and pale gums days later (onions, garlic).No safe amount of grapes is known. Onion and garlic destroy red cells; cats are more sensitive than dogs.
Human painkillersparacetamol, ibuprofen, diclofenac, aspirinBrown gums and breathlessness (paracetamol in cats); vomiting, black stool, no urine (NSAIDs).Antidotes and protection exist for some if given early (Lesson 2.1). Bring the strip.
Basis
7.8Seizures, choking, drowning and electric shock

Four emergencies in which the first instinct, to put hands on the animal, is the wrong one for the first few seconds.

4 facts
Seizure: do not restrain and do not put anything in the mouth; move furniture and people away, dim the light, time it. A fit longer than five minutes, or several in a row, is a vet-now emergency, and a fitting animal overheats. Afterwards keep it quiet and dark. In a dog of unknown history, remember rabies and avoid the saliva.
Choking: pawing at the mouth, gagging, blue gums, panic. If the object is visible at the front of the mouth, remove it; never sweep blindly at the back of the throat. If the animal collapses, a sharp upward push under the ribs, as used in people, can dislodge a ball or a bone; then the vet, because the throat swells.
Drowning: clear the mouth, hold a small animal head-down for a few seconds to drain water, dry and warm it, and go to a vet even if it seems to recover: water in the lungs causes trouble hours later.
Electric shock: monsoon wires, chewed cords. Switch off the power or move the wire with a dry wooden stick before touching the animal; burns in the mouth and fluid in the lungs appear over the following hours, so the vet sees every case.
Basis
7.9Burns, acid and firecrackers: water, and nothing else

Every burn, whether from hot water, hot tar, a firecracker on Diwali or acid thrown at a street dog, gets the same first aid: cool running water for a long time, a clean wet cover, and a vet. Everything from the kitchen makes it deeper.

4 facts
Cool running water over the burn for at least ten to twenty minutes; for acid or any chemical, keep flushing for twenty minutes or more, wearing gloves, and do not try to neutralise it with anything.
Cover loosely with a clean cloth wet with clean water. Do not break blisters, do not pull off stuck fur or fabric.
No toothpaste, oil, ghee, butter, turmeric, ice or ointments.
Keep the animal warm elsewhere; a large burn cools the whole body. Nothing by mouth if in shock. Vet the same day: burns dehydrate, get infected and hurt more than they look.
Basis
7.10Newborns and orphans: warm before you feed, and never plain cow's milk

Cold kills a newborn puppy or kitten before hunger does, and feeding a cold one kills it faster because a chilled gut cannot digest. Warm first, slowly; feed second, the right milk.

Warning5 steps
CarefulA puppy that is weak, cold and unresponsive may be hypoglycaemic. Rubbing a little honey or glucose on the gums is a stopgap a vet may advise on the telephone; it is not a feed, and the animal still needs to be seen.
  1. Warm against your body or with a wrapped hot-water bottle, over half an hour or more. A newborn's body temperature should be around 35 to 37 °C in the first week; a cold, limp puppy is not ready to feed.
  2. Feed a puppy or kitten milk replacer, or a formula a vet has given you, warmed to body heat, from a bottle or syringe held so the animal sucks belly-down, never on its back. Plain cow's milk causes diarrhoea and does not have the fat or protein they need.
  3. Every two to three hours in the first week, including nights. Small amounts; a swollen belly means too much.
  4. After each feed, rub the genitals and anus with warm damp cotton until the animal urinates and passes stool; the mother would lick. Without this they cannot.
  5. Weigh daily on a kitchen scale. Steady gain is health; a day without gain is a call to the vet.
Basis
7.11Cattle and buffalo emergencies: milk fever, bloat, calving, plastic, FMD and LSD

Large-animal first aid is mostly about position, patience and a telephone. Almost every cattle emergency below needs a vet with a needle or a tube, and what the caregiver does is keep the animal safe and upright until the vet arrives.

Do this6 facts
Do thisA downer cow is turned onto her other side every few hours, kept on deep bedding, given water she can reach, and shaded. Pressure sores and pneumonia are what kill her while the primary problem is being treated.
Milk fever: a high-yielding cow or buffalo down within three days of calving, cold ears, a neck curved back into an S, drowsy. It is calcium collapse and the vet reverses it with calcium slowly into a vein. Prop her up on her chest with bales; a cow left flat on her side bloats and inhales. Nothing by mouth while she cannot swallow.
Bloat: the left flank balloons, she stops chewing the cud, breathes hard, and may collapse. Take her off lush fodder, keep her walking and standing while the vet comes with a stomach tube or, in an emergency, a trocar. Oil drenches are a vet-guided measure and go only into an animal that can swallow.
Difficult calving: straining without progress for over an hour, or one leg and no head showing. Call the vet; do not tie ropes to a tractor. Traction must follow the calf's alignment, not the farmer's strength.
Plastic: the street cow that eats wrappers is chronically bloated, thin and off feed; the plastic is removed surgically. Prevention is a bin, not a drug.
Foot and mouth disease: blisters and raw patches in the mouth, on the tongue, between the hooves and on the teats, drooling, lameness, fever. Isolate; the vet advises a mouthwash (dilute potassium permanganate or sodium bicarbonate), soft food, a foot bath and fly control; report it, since it is notifiable, and vaccinate the rest six-monthly.
Lumpy skin disease: fever and firm nodules over the skin that ulcerate, swollen legs and lymph nodes. Isolate, control flies and ticks (which spread it), keep her eating, and the vet manages secondary infection. Vaccination is in Lesson 4.5.
Basis
7.12Birds and wildlife: a box, the dark, and a call to someone licensed

A kite tangled in kite-string on Uttarayan, a pigeon on a balcony, a fledgling on a lawn: the first aid is to contain, keep dark and quiet, and hand over. Most wild birds and animals are protected under the Wild Life (Protection) Act, and treating them is the work of licensed rescuers and the forest department.

5 facts
A cardboard box with air holes, a towel on the floor, the lid closed, in a quiet warm room. Darkness calms; a bird that can see you is a bird in shock.
No water down the beak and no food; a shocked bird inhales liquid and starves later just as well.
Do not pull glass-coated string (manja) out of a wound; cut the free ends and leave the rest for the rescuer.
A fledgling with feathers, hopping on the ground and being fed by parents, is not lost; put it back in the shrub and leave.
Telephone a wildlife rescue group or the forest department and hand the animal over the same day; keeping a protected species without permission is an offence even with good intentions.
Basis
7.13The rescue kit: what belongs in it, and what does not

A good kit is small, boring and mostly for the rescuer's own safety and the animal's transport. It contains no drug that needs a diagnosis.

Do and never

Carry

  • Nitrile gloves; a gauze roll for a muzzle; a thick towel; a torch.
  • Clean water or saline bottles; povidone-iodine; gauze pads and a crepe bandage; blunt scissors; a tick remover or fine forceps.
  • A digital thermometer and lubricant; a foldable board or a strong sheet; a blanket; a cardboard box.
  • Soap, for your own hands and any bite you receive.
  • Your own rabies pre-exposure card, and the telephone numbers: the nearest vet, the night vet, the antivenom stockist, the wildlife rescuer, the local body's dog squad.
  • A weighing sling or luggage scale, so every animal you hand to a vet comes with a weight.

Leave out

  • Antibiotics, painkillers and steroids "for emergencies". They need a diagnosis and a dose, and a car boot ruins them.
  • Vaccines and antivenom. They live in a refrigerator.
  • Turpentine, kerosene, phenyl, spirit, hydrogen peroxide, turmeric and any kitchen remedy.
  • Human cough syrups, cold tablets and paracetamol.
Basis
7.14When you are the patient: the caregiver's own bite

Every rescuer is eventually bitten or scratched. The animal's welfare does not come first at that moment; the protocol in Lesson 6.2 does, the same day, however busy the day is.

4 steps
  1. Soap and running water on the wound for fifteen minutes, then povidone-iodine. Nothing from the kitchen.
  2. The nearest anti-rabies clinic or government hospital today for the category assessment, immunoglobulin if the skin is broken, and the first vaccine dose; a tetanus dose if yours is not current.
  3. Note the animal: which one, where, its vaccination record if any, and arrange for it to be watched for ten days.
  4. Finish the course on the dates given. The failures in the national data are almost all late starts, missed immunoglobulin and unfinished courses.
Basis

Check yourself

Module 07
A dog collapses on a June afternoon, panting, gums brick red, rectal temperature 41.5 °C. The vet is thirty minutes away. What do you do first?
A cow has eaten a packet of rat-poison cakes (bromadiolone). She looks completely normal two hours later. What is the correct conclusion?
You find a cold, limp newborn puppy on a winter morning. In what order do you act?

PFA AcademyDosages: the arithmetic

A dose is a weight of drug for a weight of animal, converted into a number of tablets or millilitres. Every step in that chain can be checked with a calculator, and every step is where overdoses come from: a guessed body weight, a decimal point, a tablet of the wrong strength, "twice a day" given four hours apart. This module is the arithmetic, so that a caregiver can follow a prescription exactly and catch a mistake before the animal does.

  • Convert a mg/kg dose into tablets or millilitres for a given animal and strength, and check someone else's conversion.
  • Weigh or estimate the weight of a dog, a calf and a cow well enough to dose them.
  • Read the label ranges of the common medicines and recognise a prescription that sits outside them.
8.1Milligrams per kilogram, and the body weight everything hangs on

Almost every animal dose is written per kilogram of body weight, because a drug spreads through the animal's blood and tissue and a bigger animal has more of both. So the first number in any dose is not on the prescription at all: it is the weight of the animal, and a guessed weight makes a guessed dose.

Warning3 facts
CarefulFat and fluid do not take drugs the way muscle does. A vet doses some medicines to the animal's lean weight, and a starving dog with a swollen belly of fluid is lighter, for dosing, than the scale says. When in doubt the vet decides which weight to use.
Dogs and cats: stand on a bathroom scale holding the animal, then without it, and subtract. For a puppy or kitten, a kitchen scale in a bowl; for a large dog, a luggage scale and a sling. A colony caregiver who weighs each dog once a season has a number that a vet can use on the telephone.
Calves, goats: the same luggage-scale sling, or a weighbridge at the cooperative.
Cattle and buffalo without a scale: a tape. Measure the heart girth in centimetres, just behind the front legs, and the body length from the point of the shoulder to the pin bone. Weight in kilograms is close to girth squared, times length, divided by 10,840 (Schaeffer's formula in metric units). A cow with a 170 cm girth and a 150 cm length weighs about 170 × 170 × 150 / 10,840, which is about 400 kg.
Basis
8.2From mg/kg to tablets and millilitres: three worked examples and the decimal point

Three steps, always the same: multiply the weight by the dose per kilogram to get the milligrams; divide the milligrams by the strength to get the tablets or the millilitres; check that the answer is something you can actually measure.

3 worked examples
Example one: a tablet

A 12 kg dog, doxycycline 5 mg/kg twice a day, 100 mg tablets. 12 × 5 = 60 mg per dose. 60 ÷ 100 = 0.6 of a tablet. Half a tablet is 50 mg (4.2 mg/kg); the vet may round to half, or choose 10 mg/kg once a day, which is 120 mg, near enough one tablet. Either way the rounding is the vet's, and it stays inside the published range.

Example two: a liquid

A 20 kg dog, meloxicam 0.1 mg/kg once a day, oral suspension 1.5 mg/mL. 20 × 0.1 = 2 mg. 2 ÷ 1.5 = 1.33 mL, drawn up in a syringe. Misread the dose as 1 mg/kg and the answer becomes 13.3 mL, ten times the dose, and a dog with a bleeding stomach and failing kidneys. The decimal point is the most dangerous character on a prescription.

Example three: a livestock injection

A 400 kg cow, ivermectin 0.2 mg/kg under the skin, 1 per cent injection (10 mg/mL). 400 × 0.2 = 80 mg. 80 ÷ 10 = 8 mL. The label says the same thing as "1 mL per 50 kg". If the cow was guessed at 300 kg, she gets 6 mL and the worms survive; guessed at 500 kg, she gets 10 mL, which for this drug is tolerated, but the same guess with a narrow-margin drug is not.

Two things that can never be measured: less than a quarter of a tablet, and less than a tenth of a millilitre in an ordinary syringe. If the arithmetic produces one of these, the strength is wrong for the animal, and the answer is a lower-strength tablet or a liquid, not a knife and a guess.

Basis
8.3Frequency and duration: what "twice a day" means, and the missed-dose rule

A dose is designed to keep the drug above a working level until the next one. "Twice a day" means every twelve hours, not "morning and evening whenever". Doses bunched together overdose; doses spread out under-treat.

4 facts
Fix the clock times at the start of a course and keep them: 8 and 8, or 7 and 7. Set alarms. A colony caregiver with several dogs on courses needs a written chart.
Missed dose: give it as soon as you remember, unless the next dose is due within a few hours, in which case skip it and carry on. Never double a dose to catch up.
Duration: the number of days on the prescription is the course. Doxycycline for tick fever is 28 days because shorter courses relapse; a five-day antibiotic for a skin infection is five days because that is what was tested. Stopping early because the animal looks better is the commonest reason an infection returns worse.
Long courses of steroids, thyroid or heart medicines are not stopped when the tablets run out; they are refilled, or tapered on the vet's instruction.
Basis
8.4Check the prescription in your hand

Enter what the vet wrote and what the animal weighs; this does the multiplication and division and flags an answer that cannot be measured. It does not know any drug and never suggests a dose. If a number here disagrees with the vet's, the vet is asked, not overruled.

Checker

The checker multiplies weight by the written dose and divides by the strength. It holds no dose ranges and cannot tell whether the written dose is right for the species, the age, the kidneys or the pregnancy. That is the vet's knowledge, and Lesson 8.5 shows the published ranges only so that an obviously misplaced decimal is caught.

Basis
8.5Reference: label dose ranges of the common medicines, for reading a prescription

These are published ranges from standard veterinary formularies, given so that a prescription can be read and a tenfold error caught. The vet chooses the dose within or, for good reason, outside them. None of this is an instruction to dose an animal.

Table
MedicineClass, and how it is boughtPublished range (by mouth unless stated)Never, or only with care
Amoxicillin-clavulanateAntibiotic RxDogs and cats: 12.5 to 25 mg/kg every 12 h (of the combined product)Rabbits, guinea pigs, hamsters: never by mouth.
CefalexinAntibiotic RxDogs and cats: 20 to 30 mg/kg every 12 hPrevious penicillin or cephalosporin allergy.
DoxycyclineAntibiotic RxDogs and cats: 5 mg/kg every 12 h, or 10 mg/kg every 24 h; 28 days for ehrlichiosisGive with food and water; not with antacids, iron, calcium or milk; young animals' teeth.
EnrofloxacinAntibiotic RxDogs: 5 to 20 mg/kg a day. Cats: 5 mg/kg every 24 h, no moreGrowing puppies (cartilage); cats above 5 mg/kg (blindness).
MetronidazoleAntibiotic, antiprotozoal RxDogs: 10 to 15 mg/kg every 12 h; Giardia up to 25 mg/kg every 12 h for 5 to 7 daysPregnancy; high or long courses (neurological signs).
MeloxicamNSAID RxDogs: 0.2 mg/kg on day 1, then 0.1 mg/kg every 24 h. Cattle, buffalo: 0.5 mg/kg by injection, onceCats: far lower doses and only as prescribed. Dehydration, kidney disease, with steroids or another NSAID.
CarprofenNSAID RxDogs: 4.4 mg/kg a day, in one or two dosesCats. Same cautions as meloxicam.
PrednisoloneCorticosteroid RxAnti-inflammatory 0.5 to 1 mg/kg a day; immunosuppressive 2 to 4 mg/kg a day; tapered to stopWith NSAIDs; active infection without cover; late pregnancy.
ChlorpheniramineAntihistamine Often OTCDogs: 4 to 8 mg per dog every 8 to 12 h (about 0.4 mg/kg). Cats: 2 to 4 mg per cat every 12 hCombination cold tablets with decongestants: never.
CetirizineAntihistamine Often OTCDogs: 1 mg/kg every 12 to 24 h. Cats: 5 mg per cat every 24 hProducts combined with pseudoephedrine: never.
PraziquantelDewormer (tapeworm) OTCDogs and cats: 5 mg/kg once, repeated per the labelUnder 4 weeks of age per label.
Pyrantel pamoateDewormer (roundworm, hookworm) OTCDogs: 5 mg/kg; cats: 20 mg/kg; repeat in 2 to 3 weeksNote the species difference before reading a combination tablet.
FenbendazoleDewormer OTCDogs and cats: 50 mg/kg every 24 h for 3 days (5 days for Giardia). Goats: 7.5 to 10 mg/kg per the ICAR calendarWithdrawal periods in food animals.
IvermectinAntiparasitic Vet only in petsCattle: 0.2 mg/kg under the skin (1 mL per 50 kg of a 1 per cent solution). Dogs, for mange, off-label: 0.2 to 0.4 mg/kgCollies, Australian Shepherds, Shelties and crosses (MDR1); puppies; any dog of unknown breeding without a vet's decision.
MaropitantAntiemetic RxDogs: 1 mg/kg by injection every 24 h, or 2 mg/kg by mouth. Cats: 1 mg/kgVery young puppies and kittens per label; gut obstruction.
OndansetronAntiemetic RxDogs and cats: 0.5 to 1 mg/kg every 12 to 24 hGut obstruction.
OmeprazoleAcid blocker RxDogs and cats: 0.7 to 1 mg/kg every 24 hLong courses without a reason.
Oxytetracycline, long-actingAntibiotic, livestock RxCattle, buffalo, goats: 20 mg/kg into muscle, repeated every 48 to 72 h if neededMilk and meat withdrawal on the label; painful injection; large volumes split between sites.
AlbendazoleDewormer, livestock OTCCattle: 10 mg/kg; sheep and goats: 5 to 10 mg/kg, by mouthThe first 45 days of pregnancy (birth defects); withdrawal periods.
ParacetamolHuman analgesicNo range is given here. Some vets use it in dogs at a narrow margin; it is not for a caregiver to doseCats: never, at any dose. Dogs: never on your own.

Sources: Plumb's Veterinary Drug Handbook and the Merck Veterinary Manual, checked September 2026. Indian veterinary product labels may give slightly different figures; the label on the pack and the vet's prescription prevail.

Basis
8.6Livestock: pour-ons, drenches, injections and "one bottle per cow"

Farm medicines are dosed per kilogram like any other, but they are bought in bottles sized for a herd, which is how a habit of "one bottle for a big cow, half for a small one" grows. The label converts the dose into millilitres per 50 kg or per 10 kg; the tape and the calculator do the rest.

5 facts
Drenches (oral dewormers) are given with a drenching gun or a bottle over the tongue, slowly, head level, to an animal that is standing. Drench forced into a struggling animal goes into the lungs.
Pour-ons are measured for the weight and poured along the backline; they are absorbed through the skin and the dose is not "until it looks wet".
Injections go where the label says: under the skin of the neck, or into the neck muscle; large volumes are split between sites. The rump is avoided in meat animals.
Withdrawal is written down for milk and for meat, animal by animal (Lesson 3.6).
Deworming schedules follow the season: the ICAR goat calendar deworms before and after the monsoon, and treats for liver fluke in flood-prone districts.
Basis
8.7Why the same drug has a different dose in a different species

Dose per kilogram is not a property of the drug alone. It is the drug and the animal together, and the same molecule can need ten times more in one species than in another, or be forbidden altogether.

5 facts
Enrofloxacin: dogs up to 20 mg/kg a day; cats 5 mg/kg, because of their retina.
Pyrantel: dogs 5 mg/kg; cats 20 mg/kg, because cats absorb and clear it differently.
Xylazine, the sedative used in large-animal practice: cattle need roughly a tenth of the horse's dose per kilogram; a horse dose sedates a cow into respiratory arrest.
Ivermectin: routine in cattle at 0.2 mg/kg; the same dose in a Collie can be fatal.
Paracetamol: a human standby, a narrow-margin drug in dogs, a poison in cats.

The rule that follows: a dose you know for one species is not a dose you know for another, and a prescription written for one animal is not a prescription for its neighbour of a different species and size.

Basis

Check yourself

Module 08
A 6 kg dog is prescribed cefalexin 25 mg/kg twice a day. The pharmacy has 500 mg tablets. What should happen?
A cow's heart girth is 180 cm and her length 160 cm. Roughly how much does she weigh?
You forgot a dog's 8 pm antibiotic and remember at 1 am; the next dose is at 8 am. What is the missed-dose rule?

PFA AcademyIndications, contraindications and interactions

An indication is what a medicine is for. A contraindication is the animal, or the condition, in which it must not be given. An interaction is what two medicines do to each other inside the same animal. A vet holds all three in mind before writing a line; a caregiver who understands them can supply the facts the vet needs and question a combination that looks wrong.

  • Use the words indication, off-label, contraindication and interaction correctly.
  • Check a prescription against the animal's pregnancy, age, breed, species, kidneys and other medicines.
  • Give the food and timing rules that change whether a dose works.
9.1Indication, off-label, contraindication, side effect: the four words

Four words carry most of the safety of medicine, and they are used loosely in conversation. Here they are used exactly.

4 facts
Indication: the disease or condition a drug is licensed and shown to treat. Doxycycline is indicated for ehrlichiosis; it is not indicated for a viral cough.
Off-label (extra-label): use of a licensed medicine for a species, condition, dose or route not on its label, on a vet's professional judgement. It is common, lawful and often the only option, because few drugs are licensed for every species in India; ivermectin for canine mange and most cat medicines are off-label. It is a vet's decision because it rests on evidence the label does not carry.
Contraindication: a reason the drug must not be given. Absolute (permethrin in cats, live vaccine in a sick animal) or relative (an NSAID in an old dog whose kidneys have not been checked), where the vet weighs the risk against the need.
Side effect, toxicity, allergy: three different things. A side effect is an expected, dose-related nuisance (thirst on steroids). Toxicity is harm from too much (paracetamol in a cat). An allergy is the immune system reacting to any dose (hives after a vaccine). The response to each is different, which is why a vet asks exactly what happened.
Basis
9.2Contraindications by situation: pregnancy, age, breed, species, kidneys, liver

Read a prescription against the animal, not the disease. The table lists the situations that most often change what may be given, and the medicines that each one rules out or restricts.

Table
SituationRules out or restrictsWhy
PregnancyEnrofloxacin and other fluoroquinolones; metronidazole; albendazole in the first 45 days (cattle, sheep); dexamethasone and other steroids in late-pregnant cattle and buffalo; live vaccines unless the label allows; most sedativesBirth defects in the young; dexamethasone starts labour and causes abortion in cattle.
Growing animalsFluoroquinolones in puppies (large breeds until about 12 to 18 months); tetracyclines before the adult teeth are inCartilage damage; permanent tooth staining.
Kidney disease, dehydration, shockAll NSAIDs; aminoglycosides; some antibiotics need a lower doseThe kidney depends on prostaglandins that NSAIDs remove; aminoglycosides are directly toxic to it.
Liver diseaseParacetamol; ketoconazole and other azoles; some sedatives; high-dose NSAIDsThe liver clears them; a failing liver lets them accumulate.
MDR1 (ABCB1) breeds: Collies, Australian Shepherds, Shelties, Old English Sheepdogs and their crossesIvermectin and related drugs at mange doses; loperamide; some chemotherapy and sedativesA missing pump lets the drug into the brain.
CatsParacetamol; aspirin; permethrin and other concentrated pyrethroids; amitraz; phenol disinfectants (Dettol, phenyl); benzyl alcohol; enrofloxacin above 5 mg/kg; most human NSAIDsMissing liver enzymes; a retina that fluoroquinolones damage.
Horses and donkeysLincomycin, clindamycin, oral penicillins and macrolides; tilmicosin (fatal by injection to horses, and to people)Fatal colitis; cardiac toxicity.
Rabbits, guinea pigs, hamstersOral penicillins, cephalosporins, lincomycin, clindamycinThey wipe out the gut flora and the animal dies of the overgrowth.
Flat-faced breeds, heart diseaseSedatives and anaesthetics only with a vet's assessment; anything that depresses breathingAirways that are already narrow; a heart that cannot compensate.
Food-producing animalsColistin (banned); diclofenac, ketoprofen, aceclofenac, nimesulide (banned); chloramphenicol and nitrofurans in food animals; every drug carries a withdrawalResidues in milk and meat; vultures; the law.
Basis
9.3Interactions that matter: the pairs that fight

Most animals on medicine are on more than one, and a caregiver often sees medicines from two vets, a chemist and a neighbour arrive in the same bowl. These are the combinations that cause harm often enough to be worth knowing by name.

Do thisTable
Do thisKeep one list, on paper or a phone, of everything each animal is receiving: prescribed, over the counter, spot-on, dewormer, supplement, home remedy. Show it at every visit. Most interactions are caught by a list, not by memory.
PairWhat happensWhat to do
NSAID + corticosteroidmeloxicam and prednisolone; the injection of both at one visitStomach and gut ulcers, bleeding, kidney injury.Not given together. If an animal on one is prescribed the other by a second vet, say so before the first dose.
NSAID + NSAIDcarprofen and meloxicam; a vet's NSAID and a human one from the cupboardThe same, doubled. Switching from one NSAID to another needs a washout of several days.One NSAID at a time, and the vet sets the washout.
NSAID + ACE inhibitor or diureticenalapril, furosemide in a heart patientKidney failure, especially if the animal is dehydrated.The vet chooses; blood tests before and during.
Doxycycline or other tetracycline + antacid, iron, calcium, milk, curdThe mineral binds the antibiotic in the gut and it is not absorbed. The course fails.Two hours apart. Doxycycline with a little food and water, not with a bowl of milk.
Enrofloxacin + antacid, sucralfate, iron, dairyNot absorbed, as above.Two hours apart.
Enrofloxacin + theophyllineTheophylline levels rise to toxic.The vet lowers the theophylline or changes the antibiotic.
Ivermectin + ketoconazole, itraconazole, spinosad, or some heart drugsThe second drug blocks the pump that keeps ivermectin out of the brain: tremors, blindness, coma, even in non-MDR1 dogs.Vet decides; the flea product spinosad is the one owners combine by accident.
Metronidazole + phenobarbitalMetronidazole clears faster and under-treats; sedation adds up.Vet adjusts.
Aminoglycoside (gentamicin) + furosemide or an NSAIDKidney damage and deafness multiply.Hospital use only, with fluids.
Tramadol or other serotonergic drugs + selegiline, fluoxetine, other antidepressantsSerotonin syndrome: agitation, tremor, fever, seizures.Tell the vet every behaviour or pain drug the animal takes.
Vaccine + high-dose steroid, chemotherapy, or another immunosuppressantThe vaccine does not take.Vaccinate before treatment or after it, on the vet's timing.
Sedative + sedativexylazine, ketamine, acepromazine, diazepam, an antihistamine on topBreathing and blood pressure fall further than either alone.Sedation is a vet's procedure, never a home one.
Basis
9.4Food and timing: with food, without food, two hours apart

Whether a tablet goes in with the meal or an hour before it changes how much is absorbed and what it does to the stomach. The label says; the rules below are the common ones.

5 facts
With food: all NSAIDs (stomach protection); doxycycline (a little food and a chaser of water so it does not lodge in the gullet, which matters most in cats); metronidazole (taste, nausea); most antibiotics tolerate food and absorb well.
Without food, an hour before: levothyroxine (thyroid); some dewormers per label; sucralfate.
Two hours apart: tetracyclines and fluoroquinolones from antacids, iron, calcium, milk and curd; sucralfate from everything.
Never in the bowl unnoticed: a tablet hidden in food may be eaten by the wrong animal in a multi-dog household or colony, or left behind when the sick one does not eat. Watch it go down.
Liquids: shake suspensions every time; measure with a syringe, not a spoon.
Basis
9.5What the vet needs to know before prescribing, and should be told without being asked

Every contraindication and interaction on this page turns on a fact the vet may not have unless someone says it. In a busy Indian clinic, the caregiver is often the only one who knows.

7 steps
  1. Species, breed or type, sex, and whether the female may be pregnant or is feeding young.
  2. Age, or the best guess, and weight.
  3. Every medicine given in the last month, including spot-ons, dewormers, a neighbour's tablet and a home remedy.
  4. Any earlier reaction: swelling after a vaccine, vomiting on an antibiotic, a Collie type that went wobbly on ivermectin.
  5. Any known disease: kidneys, liver, heart, diabetes, epilepsy.
  6. For a farm animal: whether her milk is sold, and when she is due to calve or kid.
  7. Whether the animal can be dosed by mouth at all, how often someone will be present, and whether it will be watched after an injection.
Basis
9.6When a medicine goes wrong: what to keep, what to say, where it is reported

An animal that reacts badly to a medicine needs two things: treatment for the reaction, and a record that lets the next animal avoid it.

4 facts
Stop the drug unless the vet says otherwise, and telephone: what was given, how much, when, and what the animal is doing now (Lesson 10.4).
Keep the pack, the strip or the vial, with the batch number and expiry visible, and photograph the animal's signs.
Write it on the animal's record, and if it is a colony dog, on the card that travels with it.
Reporting: suspected reactions to a licensed veterinary product are reported by the vet to the manufacturer (the pack carries the contact) and to the State drugs control authority; the batch number is what makes the report useful. A substandard or spurious product is a matter for the drugs inspector under the Drugs and Cosmetics Act.
Basis

Check yourself

Module 09
A dog on doxycycline is given the tablet crushed into a bowl of curd each morning. Why might the course fail?
A buffalo eight months pregnant has a swollen udder and a fever. A neighbour suggests a dexamethasone injection "to bring the swelling down". What is the danger?

PFA AcademyDo's and Don'ts

Everything above, compressed to the sentences worth pinning to a wall. The first two lessons are the list. The third audits what Indian kitchens actually put on animals. The last is the script that gets a vet to help you in the first minute of a call.

  • State the essential rules of animal medicine without looking them up.
  • Say which household remedies are harmless, which are useless and which kill.
  • Describe an emergency to a vet on the telephone in ten sentences.
10.1The essential list

Thirty sentences. The Do's are about weight, records, timing and the vet. The Don'ts are about the kitchen, the cupboard and the neighbour.

Do and never

Do

  • Weigh the animal. Every dose starts there.
  • Read the molecule, the strength and the weight aloud before every first dose.
  • Give a prescribed course exactly: dose, route, clock time, number of days.
  • Keep one written list of everything each animal receives, and show it at every visit.
  • Vaccinate in series, on schedule, from a cold vial, into a healthy animal; write down the batch.
  • Deworm on schedule, and before vaccinating.
  • Use tick and flea products for the right species and weight band, and keep treated dogs from cats.
  • Wash wounds with clean water in quantity, then diluted povidone-iodine; cover; see a vet.
  • Cool a heatstroke case where it is, then move it.
  • Keep a snakebitten animal still and go straight to antivenom.
  • Warm a cold newborn before feeding it, and feed it the right milk.
  • Ask "when can I sell the milk?" after every injection into a milking animal.
  • Take rabies pre-exposure vaccination yourself, and treat every bite you get the same day.
  • Photograph wounds and reactions; note dates and times.
  • Ask the vet the question you are embarrassed to ask. The embarrassing question is the safe one.

Don't

  • Give a human painkiller to a dog or cat. Paracetamol kills cats; ibuprofen and diclofenac kill dogs.
  • Give a leftover antibiotic, or one dog's course to another.
  • Combine a steroid and an NSAID, or two NSAIDs.
  • Put permethrin, deltamethrin, amitraz, Dettol or phenyl on a cat.
  • Give ivermectin to a Collie-type dog, or to any dog, without a vet.
  • Stop a course early because the animal looks better, or double a dose to catch up.
  • Split one vaccine dose between two animals, or give one shot and call a puppy vaccinated.
  • Put turmeric, lime, chilli, oil, ghee, kerosene, turpentine or toothpaste on any wound or burn.
  • Tie a tourniquet, cut, suck or ice a snakebite, or wait for symptoms.
  • Lay wet towels over a heatstroke dog, or drive first and cool later.
  • Induce vomiting with salt, or at all without a vet's instruction.
  • Feed plain cow's milk to a newborn puppy or kitten.
  • Inject oxytocin into a cow for milk, or a hormone into a dog instead of sterilising her.
  • Sell milk inside the withdrawal period, or use colistin, diclofenac, ketoprofen, aceclofenac or nimesulide in an animal.
  • Handle a drooling, staggering or strangely quiet dog with bare hands, or keep a wild animal you found.
Basis
10.2The kitchen audit: what Indian households put on animals, and whether it helps

Most home remedies are neither medicine nor poison; they are delay. A few are poison. The table separates them, so that the harmless ones can stop being argued about and the dangerous ones can stop being used.

Table
RemedyVerdictWhy
Turmeric (haldi) on a woundUseless and harmfulSeals in dirt and bacteria, hides the wound from the vet, and belongs with the herbs and irritants the rabies guidelines say never to put on a bite. Fine in food.
Neem leaves, neem oilMild; not a cureA weak repellent and antiseptic. Does not cure mange, tick fever or maggots. Neem oil on cats and in quantity on puppies: no.
Coconut oilHarmless; not a medicineFine on dry skin. Traps heat on a burn. Does nothing for infection.
Ghee, butter, toothpaste on burnsHarmfulTraps heat and bacteria. Cool running water is the treatment.
MilkDependsNot a food for adult dogs and cats in quantity (lactose); never as a newborn's replacer. A splash in a bowl for an adult that tolerates it does no harm.
Curd, rice, boiled chickenUsefulA bland recovery diet a vet will often suggest. Not a treatment for the cause of the diarrhoea.
Salt, to induce vomitingDangerousSalt poisoning and brain swelling. Never.
Lime (chuna), chilli, tobacco, betel on woundsDangerousChemical burns; nicotine poisoning from tobacco. Chillies, lime and betel leaves are on the rabies guidelines' list of things never to put on a bite.
Dettol, Savlon, phenyl, LizolDangerous to cats; wrong on woundsPhenolic and chloroxylenol disinfectants are toxic to cats, and undiluted they kill tissue in any wound. For floors, rinse well before a cat walks on them.
Kerosene, petrol, turpentine on maggotsHarmfulBurns tissue, poisons through the skin, does not clear the wound. The larvae must be removed.
Garlic, onion "for worms" or in foodDangerousDestroy red blood cells in dogs and cats over days. Not a dewormer.
Honey or glucose on the gumsStopgap onlyRaises blood sugar in a collapsed puppy for a few minutes while you reach a vet; not a feed and not a treatment.
Camphor, Vicks, eucalyptus, tea-tree and other essential oilsDangerousToxic to cats and to small dogs, by skin and by breath.
Ice on burns, snakebite or heatstrokeHarmfulDeepens burns, worsens snakebite tissue death, and overshoots heatstroke cooling. Running water is right for burns; flowing water and air for heat.
Ayurvedic or herbal tablets sold "for pets"UnknownNo dose, no species data, no withdrawal. Ask the vet before adding anything to a course.
Basis
10.3Ten sentences that get a vet to help you fast

A vet on the telephone at midnight decides in the first thirty seconds whether to say "bring it now" or "watch it till morning". These ten sentences, in this order, give them what that decision needs.

10 steps
  1. "It is a dog (cat, calf, goat), about 12 kg, about two years old, female, not spayed."
  2. "What happened: hit by a two-wheeler at about 9 pm" (or: found weak this morning; bitten by a snake; ate rat poison).
  3. "Now it is: conscious but not standing, breathing fast, about 60 a minute."
  4. "Gums are pale pink and slow to refill" (or white, or blue, or red).
  5. "Temperature is 40.3" (or: I could not take it).
  6. "Bleeding: from the left hind leg, controlled with pressure" (or none seen).
  7. "Vomiting or diarrhoea: vomited twice, no blood."
  8. "Given so far: nothing" (or exactly what, how much, and when).
  9. "History: vaccinated for rabies in March, on doxycycline since last week, no known illness."
  10. "I can be at the clinic in twenty minutes; what should I do on the way?"

Then listen, and do what the vet says on the way, including the things that feel like doing nothing: keeping the animal flat, warm, quiet and unfed.

Basis
10.4Where this Academy stops, and the law starts

This page teaches how to read and follow medicine, not how to practise it. Three laws draw the line, and knowing them protects the caregiver as much as the animal.

3 facts
The Indian Veterinary Council Act 1984 reserves veterinary practice, including choosing drugs and doses, to registered veterinary practitioners. Following a prescription and giving first aid are not practice.
The Animal Birth Control Rules 2023 make sterilisation and vaccination under a veterinarian the lawful way to manage community dogs, and give caregivers a recognised role in presenting dogs and keeping records.
The Prevention of Cruelty to Animals Act 1960 makes cruelty, including injurious injections to force lactation, an offence; a person who sees it can report it through the Laws page on this site.

A vet who is asked good questions gives better care. That is the whole purpose of the ten modules above.

Basis

Check yourself

Module 10
Which of these kitchen items is dangerous to give a dog, rather than merely useless?
You are calling a vet about a collapsed dog. Which opening gives the vet the most?

What changed, 2019 to 2026

The rules moved. The habits have not caught up.

Six changes that a caregiver, a farmer or a village vet may not have heard of, each of which alters what is safe or lawful to do today.

Nimesulide banned for animals, 2025

The fourth NSAID removed from veterinary use for the sake of vultures, after diclofenac (2006), ketoprofen and aceclofenac (2023). Meloxicam is the lawful alternative in cattle.

Colistin out of the food chain, 2019

Prohibited for food-producing animals, poultry, aquaculture and feed. A last-resort human antibiotic that Indian poultry had been eating as a growth promoter.

Animal Birth Control Rules, 2023

Sterilisation plus anti-rabies vaccination, ear-notching and return became the lawful management of community dogs, with a recognised role for caregivers.

WSAVA vaccination guidelines, 2024

The puppy and kitten series now ends at 16 weeks or later with an extra dose at 26 weeks; core boosters no more than every three years; leukaemia vaccine recommended for kittens and outdoor cats.

Rabies monoclonal antibodies, 2016 and 2019

Rabishield and TwinRab give India two lab-made alternatives to horse and human rabies immunoglobulin, with fixed doses per kilogram and no serum reactions.

Heatstroke: cool first, transport second

Emergency guidance reversed the old advice. Wet towels and "tepid water" are out; water over the whole body, airflow, and immersion for a young healthy dog are in.

Sources

Every lesson rests on one of these.

The chips under each lesson name the source it rests on; click one to see every lesson that shares it. The documents themselves are here. Where an Indian product label and an international formulary disagree, the label on the pack and the vet's prescription prevail.

Rabies

National Guidelines on Rabies Prophylaxis, National Centre for Disease Control, Ministry of Health and Family Welfare. Wound care, categories, immunoglobulin doses, the Essen and intradermal schedules, storage limits.

Companion-animal vaccination

WSAVA Guidelines for the Vaccination of Dogs and Cats, 2024. Core and non-core vaccines, the puppy and kitten series, maternal antibody, titre testing.

Cattle and buffalo

NDDB Dairy Knowledge Portal vaccination schedule, and the Department of Animal Husbandry and Dairying's National Animal Disease Control Programme for FMD and brucellosis.

Goats and sheep

ICAR Central Institute for Research on Goats, health calendar. Vaccination, deworming and dipping by month.

Clinical reference

The Merck Veterinary Manual for vital signs, toxicology, species differences and first aid; Plumb's Veterinary Drug Handbook for the label dose ranges in Module 08.

Indian regulation

The Drugs and Cosmetics Act 1940 and Rules 1945 (Schedules H and H1); the Section 26A prohibitions on veterinary diclofenac (2006), ketoprofen and aceclofenac (2023), nimesulide (2025) and colistin in food animals (2019); the Indian Veterinary Council Act 1984; the Animal Birth Control Rules 2023; and the Prevention of Cruelty to Animals Act 1960, all of which are on the Laws page with the text.

Antivenom

Product literature of the Central Research Institute, Kasauli, and Haffkine Bio-Pharmaceutical for Indian polyvalent anti-snake venom serum; the WHO guidelines on the management of snakebite in South-East Asia; a published Russell's viper case report from a Karnataka veterinary college hospital.

Heatstroke

The Veterinary Committee on Trauma's cooling guidance and the Royal Veterinary College's "cool first, transport second" advice, both of which changed the first aid in Module 07.